Abstract
Caged cell-culturing substrate is composed of a glass substrate immobilized with a monolayer having a photocleavable protecting group. This substrate can be activated for cell adhesion by illumination of light. By using this substrate, we have succeeded in micropatterning of cells corresponding to photomasks inserted at the location of the field diaphragm of a standard fluorescence microscope. In the present study, we evaluated the effect of terminal functional groups in caged cell-culturing substrates on photoactivation of cell adhesion without using fibronectin. In addition, we applied one of the substrates to navigate migration of single cells from their original pattern by illumination of light.
Original language | English |
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Pages | 5197-5198 |
Number of pages | 2 |
Publication status | Published - 2005 |
Event | 54th SPSJ Symposium on Macromolecules - Yamagata, Japan Duration: 2005 Sept 20 → 2005 Sept 22 |
Other
Other | 54th SPSJ Symposium on Macromolecules |
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Country/Territory | Japan |
City | Yamagata |
Period | 05/9/20 → 05/9/22 |
Keywords
- Caged compounds
- Cell adhesion
- Cell migration
- Light
- Monolayer
- Patterning
ASJC Scopus subject areas
- Engineering(all)