Cellular responses to electrochemical killing process by applying a constant potential in synchronously cultured Saccharomyces Cerevisiae

Haruko Takeyama, Takeyuki Suzuki, Yoshiko Okamura, Tetsushi Mori, Tadashi Matsunaga

Research output: Contribution to journalArticle

Abstract

To elucidate the mechanism of the electrochemical killing, the global gene expression of synchronously cultured Saccharomyces cerevisiae exposed to electrochemical stimulus was analyzed using DNA microarray. By applying a potential of 1.0 V vs. saturated calomel electrode (SCE), oxidative stress related genes were expressed after only 5 minutes. The gene for cta1 exhibited the highest expression level, while ROS gradually accumulated inside the cells. Genes for signal transduction which may be related to cellular apoptosis were also seen expressed.

Original languageEnglish
Pages (from-to)603-605
Number of pages3
JournalElectrochemistry
Volume76
Issue number8
DOIs
Publication statusPublished - 2008 Aug
Externally publishedYes

Keywords

  • Electrochemical killing process
  • Synchronous culture
  • Transcriptome

ASJC Scopus subject areas

  • Electrochemistry

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