Central mechanisms for thermoregulation in a hot environment

    Research output: Contribution to journalArticle

    29 Citations (Scopus)

    Abstract

    Homeothermic animals regulate body temperature by autonomic and behavioral thermoeffector responses. The regulation is conducted mainly in the brain. Especially, the preoptic area (PO) in the hypothalamus plays a key role. The PO has abundant warm-sensitive neurons, sending excitatory signals to the brain regions involved in heat loss mechanisms, and inhibitory signals to those involved in heat production mechanisms. The sympathetic fibers determine tail blood flow in rats, which is an effective heat loss process. Some areas in the midbrain and medulla are involved in the control of tail blood flow. Recent study also showed that the hypothalamus is involved in heat escape behavior in rats. However, our knowledge about behavioral regulation is limited. The central mechanism for thermal comfort and discomfort, which induce various behavioral responses, should be clarified. In the heat, dehydration affects both autonomic and behavioral thermoregulation by non-thermoregulatory factors such as high Na+ concentration. The PO seems to be closely involved in these responses. The knowledge about the central mechanisms involved in thermoregulation is important to improve industrial health, e.g. preventing accidents associated with the heat or organizing more comfortable working environment.

    Original languageEnglish
    Pages (from-to)359-367
    Number of pages9
    JournalIndustrial Health
    Volume44
    Issue number3
    DOIs
    Publication statusPublished - 2006 Jul

    Fingerprint

    thermoregulation
    Body Temperature Regulation
    behavioral response
    brain
    Hot Temperature
    blood
    escape behavior
    Preoptic Area
    heat production
    body temperature
    Heat losses
    dehydration
    accident
    Rats
    Brain
    Blood
    Hypothalamus
    Thermal comfort
    Tail
    animal

    Keywords

    • Autonomic thermoregulation
    • Behavioral thermoregulation
    • Brain stem
    • Heat
    • Hypothalamus
    • Preoptic area
    • Saliva
    • Tail blood flow

    ASJC Scopus subject areas

    • Environmental Science(all)
    • Environmental Chemistry
    • Public Health, Environmental and Occupational Health
    • Toxicology
    • Health, Toxicology and Mutagenesis

    Cite this

    Central mechanisms for thermoregulation in a hot environment. / Nagashima, Kei.

    In: Industrial Health, Vol. 44, No. 3, 07.2006, p. 359-367.

    Research output: Contribution to journalArticle

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