Changes in heart rate with refeeding in anorexia nervosa: A pilot study

Nahoko (Miyasaka) Yoshida, Kazuhiro Yoshiuchi, Hiroaki Kumano, Tadashi Sasaki, Tomifusa Kuboki

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objective: To find differences in heart rate before and after refeeding and to identify which parameters of autonomic activity and endocrine function are associated with these differences. Methods: Before and after the start of refeeding, body weight, RR interval (RRI), heart rate variability, endocrine function, and energy expenditure were measured in nine female anorexia nervosa patients. Results: After short-term refeeding, mean daytime heart rate rose from 54.9 to 69.4 bpm (P<.05). The changes in sympathetic activity were correlated negatively with the changes in RRI (r=-.933, P<.001). Urine C-peptide, IGF-1, and fT3 increased significantly, and norepinephrine tended to increase. Conclusion: We demonstrated that autonomic nervous activity was relevant to changes in heart rate during refeeding, and it is speculated that the increases in insulin secretion, thyroid function, and IGF-1 were responsible for the mechanisms.

Original languageEnglish
Pages (from-to)571-575
Number of pages5
JournalJournal of Psychosomatic Research
Volume61
Issue number4
DOIs
Publication statusPublished - 2006 Oct
Externally publishedYes

Fingerprint

Anorexia Nervosa
Heart Rate
Insulin-Like Growth Factor I
C-Peptide
Energy Metabolism
Norepinephrine
Thyroid Gland
Body Weight
Urine
Insulin

Keywords

  • Anorexia nervosa
  • Heart rate
  • Parasympathetic activity
  • Refeeding
  • Sympathetic nervous activity

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry
  • Psychology(all)

Cite this

Changes in heart rate with refeeding in anorexia nervosa : A pilot study. / Yoshida, Nahoko (Miyasaka); Yoshiuchi, Kazuhiro; Kumano, Hiroaki; Sasaki, Tadashi; Kuboki, Tomifusa.

In: Journal of Psychosomatic Research, Vol. 61, No. 4, 10.2006, p. 571-575.

Research output: Contribution to journalArticle

Yoshida, Nahoko (Miyasaka) ; Yoshiuchi, Kazuhiro ; Kumano, Hiroaki ; Sasaki, Tadashi ; Kuboki, Tomifusa. / Changes in heart rate with refeeding in anorexia nervosa : A pilot study. In: Journal of Psychosomatic Research. 2006 ; Vol. 61, No. 4. pp. 571-575.
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