Changes in male brain responses to emotional faces from adolescence to middle age

Quinton Deeley, Eileen M. Daly, Rayna Azuma, Simon Surguladze, Vincent Giampietro, Michael J. Brammer, Brian Hallahan, Robin I M Dunbar, Mary L. Phillips, Declan G M Murphy

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Facial emotion perception is fundamental to human social behaviour, and changes with age. Nevertheless, age-related differences in the relative activation of components of emotion processing networks are poorly understood. Thus we measured brain activity with event-related fMRI in 40 right handed healthy male controls, age range 8-50 years, during implicit processing of fearful, disgusted, and a control condition of neutral facial expressions. There was a significant negative correlation between increasing age and neural response to fearful and disgusted expressions in dorsomedial prefrontal cortex (BA 10), and middle frontal gyri (BA 6). Hence, in healthy subjects, the functional anatomy of facial emotion processing is not 'hard-wired', but undergoes progressive change into adulthood. Possible explanations for the age-related changes in dorsomedial and middle frontal cortical activity may include a reduction in the attentional demands of appraising facial expressions as perceptual skill increases, or changes in processing the self-relevance of facial expressions during social and cognitive development.

Original languageEnglish
Pages (from-to)389-397
Number of pages9
JournalNeuroImage
Volume40
Issue number1
DOIs
Publication statusPublished - 2008 Mar 1
Externally publishedYes

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Facial Expression
Emotions
Brain
Social Behavior
Prefrontal Cortex
Social Change
Anatomy
Healthy Volunteers
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Neurology

Cite this

Deeley, Q., Daly, E. M., Azuma, R., Surguladze, S., Giampietro, V., Brammer, M. J., ... Murphy, D. G. M. (2008). Changes in male brain responses to emotional faces from adolescence to middle age. NeuroImage, 40(1), 389-397. https://doi.org/10.1016/j.neuroimage.2007.11.023

Changes in male brain responses to emotional faces from adolescence to middle age. / Deeley, Quinton; Daly, Eileen M.; Azuma, Rayna; Surguladze, Simon; Giampietro, Vincent; Brammer, Michael J.; Hallahan, Brian; Dunbar, Robin I M; Phillips, Mary L.; Murphy, Declan G M.

In: NeuroImage, Vol. 40, No. 1, 01.03.2008, p. 389-397.

Research output: Contribution to journalArticle

Deeley, Q, Daly, EM, Azuma, R, Surguladze, S, Giampietro, V, Brammer, MJ, Hallahan, B, Dunbar, RIM, Phillips, ML & Murphy, DGM 2008, 'Changes in male brain responses to emotional faces from adolescence to middle age', NeuroImage, vol. 40, no. 1, pp. 389-397. https://doi.org/10.1016/j.neuroimage.2007.11.023
Deeley, Quinton ; Daly, Eileen M. ; Azuma, Rayna ; Surguladze, Simon ; Giampietro, Vincent ; Brammer, Michael J. ; Hallahan, Brian ; Dunbar, Robin I M ; Phillips, Mary L. ; Murphy, Declan G M. / Changes in male brain responses to emotional faces from adolescence to middle age. In: NeuroImage. 2008 ; Vol. 40, No. 1. pp. 389-397.
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