Characterization of hybridization on diamond solution-gate field-effect transistors for detecting single mismatched oligonucleotides

Jung Hoon Yang, Shouma Kuga, Kwang Soup Song, Hiroshi Kawarada

    Research output: Contribution to journal › Article

    4 Citations (Scopus)

    Abstract

    Using diamond field-effect transistors (FETs) operated in electrolyte solution (solution-gate FETs; SGFETs), a label-free charge detection method between complementary and single mismatched target oligonucleotides is proposed. The probe oligonucleotides immobilized at the activated carboxyl groups of carboxylic aromatic compounds (CACs) on the previously formed amino groups of the diamond surface. The high performance of the diamond surface for oligonucleotides detection was studied with respect to selectivity, sensitivity, and reproducibility of the diamond SGFETs.

    Original languageEnglish
    Pages (from-to)1180011-1180013
    Number of pages3
    JournalApplied Physics Express
    Volume1
    Issue number11
    DOIs
    Publication statusPublished - 2008 Nov

    Fingerprint

    Gates (transistor)
    oligonucleotides
    Oligonucleotides
    Diamonds
    field effect transistors
    diamonds
    aromatic compounds
    Aromatic compounds
    carboxyl group
    Field effect transistors
    Labels
    selectivity
    Electrolytes
    electrolytes
    probes
    sensitivity

    ASJC Scopus subject areas

    • Engineering(all)
    • Physics and Astronomy(all)

    Cite this

    Characterization of hybridization on diamond solution-gate field-effect transistors for detecting single mismatched oligonucleotides. / Yang, Jung Hoon; Kuga, Shouma; Song, Kwang Soup; Kawarada, Hiroshi.

    In: Applied Physics Express, Vol. 1, No. 11, 11.2008, p. 1180011-1180013.

    Research output: Contribution to journal › Article

    Yang, JH, Kuga, S, Song, KS & Kawarada, H 2008, 'Characterization of hybridization on diamond solution-gate field-effect transistors for detecting single mismatched oligonucleotides', Applied Physics Express, vol. 1, no. 11, pp. 1180011-1180013. https://doi.org/10.1143/APEX.1.118001
    Yang JH, Kuga S, Song KS, Kawarada H. Characterization of hybridization on diamond solution-gate field-effect transistors for detecting single mismatched oligonucleotides. Applied Physics Express. 2008 Nov;1(11):1180011-1180013. https://doi.org/10.1143/APEX.1.118001
    Yang, Jung Hoon ; Kuga, Shouma ; Song, Kwang Soup ; Kawarada, Hiroshi. / Characterization of hybridization on diamond solution-gate field-effect transistors for detecting single mismatched oligonucleotides. In: Applied Physics Express. 2008 ; Vol. 1, No. 11. pp. 1180011-1180013.
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