Characterization of poly(N-isopropylacrylamide) gel grafted polydimethylsiloxane as temperature-responsive cell culture substrate

Yoshikatsu Akiyama, Miki Matsuyama, Naoya Takeda, Masayuki Yamato, Teruo Okano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Poly(N-isopropylacrylamide) (PIPAAm) hydrogel modified poly(dimethylsiloxane) (PDMS) surface (PIPAAm-PDMS) was prepared as a new temperature-responsive cell culture surface by using electron beam (EB) irradiation method. PIPAAm-PDMS surface properties at unstretched and stretched states were characterized by using various analytical method. As the result, we found that PIPAAm-PDMS surface properties as well as thickness of the grafted PIPAAm gel were altered by applied uniaxial mechanical stretching stress. The mechanical stress can affect the degree of hydration of grafted PIPAAm chains.

Original languageEnglish
Title of host publication2016 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781509027842
DOIs
Publication statusPublished - 2017 Jan 18
Externally publishedYes
Event27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016 - Nagoya, Japan
Duration: 2016 Nov 282016 Nov 30

Other

Other27th International Symposium on Micro-NanoMechatronics and Human Science, MHS 2016
CountryJapan
CityNagoya
Period16/11/2816/11/30

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Biomedical Engineering
  • Mechanical Engineering
  • Human-Computer Interaction
  • Instrumentation
  • Computer Science Applications
  • Biotechnology
  • Artificial Intelligence

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