Chemo-mechanical coupling in the rotary molecular motor f1-atpase

Kengo Adachi; Shou Furuike; Mohammad Delawar Hossain; Hiroyasu Itoh; Kazuhiko Kinosita; Yasuhiro Onoue; Rieko Shimo-Kon

Chemo-mechanical coupling in the rotary molecular motor f1-atpase

Kengo Adachi, Shou Furuike, Mohammad Delawar Hossain, Hiroyasu Itoh, Kazuhiko Kinosita, Yasuhiro Onoue, Rieko Shimo-Kon

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

F1-ATPase is a molecular motor in which the central γ subunit rotates inside the cylinder made of α3β₃ subunits. The rotation is powered by ATP hydrolysis in three catalytic sites, and reverse rotation of the γ subunit by an external force leads to ATP synthesis in the catalytic sites. Single-molecule studies have revealed how the mechanical rotation is coupled to the chemical reactions in the three catalytic sites: binding/release of ATP, ADP, and phosphate, and hydrolysis/synthesis of ATP.

Original language	English
Title of host publication	Springer Series in Chemical Physics
Pages	272-285
Number of pages	14
Volume	96
Publication status	Published - 2010
Externally published	Yes

Publication series

Name	Springer Series in Chemical Physics
Volume	96
ISSN (Print)	01726218

ASJC Scopus subject areas

Physical and Theoretical Chemistry

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Chemo-mechanical coupling in the rotary molecular motor f1-atpase. / Adachi, Kengo; Furuike, Shou; Hossain, Mohammad Delawar; Itoh, Hiroyasu; Kinosita, Kazuhiko; Onoue, Yasuhiro; Shimo-Kon, Rieko.

Springer Series in Chemical Physics. Vol. 96 2010. p. 272-285 (Springer Series in Chemical Physics; Vol. 96).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

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AU - Onoue, Yasuhiro

AU - Shimo-Kon, Rieko

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