Abstract
F1-ATPase is a molecular motor in which the central γ subunit rotates inside the cylinder made of α3β3 subunits. The rotation is powered by ATP hydrolysis in three catalytic sites, and reverse rotation of the γ subunit by an external force leads to ATP synthesis in the catalytic sites. Single-molecule studies have revealed how the mechanical rotation is coupled to the chemical reactions in the three catalytic sites: binding/release of ATP, ADP, and phosphate, and hydrolysis/synthesis of ATP.
| Original language | English |
|---|---|
| Title of host publication | Springer Series in Chemical Physics |
| Pages | 272-285 |
| Number of pages | 14 |
| Volume | 96 |
| Publication status | Published - 2010 |
| Externally published | Yes |
Publication series
| Name | Springer Series in Chemical Physics |
|---|---|
| Volume | 96 |
| ISSN (Print) | 01726218 |
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ASJC Scopus subject areas
- Physical and Theoretical Chemistry
Cite this
Chemo-mechanical coupling in the rotary molecular motor f1-atpase. / Adachi, Kengo; Furuike, Shou; Hossain, Mohammad Delawar; Itoh, Hiroyasu; Kinosita, Kazuhiko; Onoue, Yasuhiro; Shimo-Kon, Rieko.
Springer Series in Chemical Physics. Vol. 96 2010. p. 272-285 (Springer Series in Chemical Physics; Vol. 96).Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Chemo-mechanical coupling in the rotary molecular motor f1-atpase
AU - Adachi, Kengo
AU - Furuike, Shou
AU - Hossain, Mohammad Delawar
AU - Itoh, Hiroyasu
AU - Kinosita, Kazuhiko
AU - Onoue, Yasuhiro
AU - Shimo-Kon, Rieko
PY - 2010
Y1 - 2010
N2 - F1-ATPase is a molecular motor in which the central γ subunit rotates inside the cylinder made of α3β3 subunits. The rotation is powered by ATP hydrolysis in three catalytic sites, and reverse rotation of the γ subunit by an external force leads to ATP synthesis in the catalytic sites. Single-molecule studies have revealed how the mechanical rotation is coupled to the chemical reactions in the three catalytic sites: binding/release of ATP, ADP, and phosphate, and hydrolysis/synthesis of ATP.
AB - F1-ATPase is a molecular motor in which the central γ subunit rotates inside the cylinder made of α3β3 subunits. The rotation is powered by ATP hydrolysis in three catalytic sites, and reverse rotation of the γ subunit by an external force leads to ATP synthesis in the catalytic sites. Single-molecule studies have revealed how the mechanical rotation is coupled to the chemical reactions in the three catalytic sites: binding/release of ATP, ADP, and phosphate, and hydrolysis/synthesis of ATP.
UR - http://www.scopus.com/inward/record.url?scp=78650186673&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650186673&partnerID=8YFLogxK
M3 - Chapter
AN - SCOPUS:78650186673
SN - 9783642025969
VL - 96
T3 - Springer Series in Chemical Physics
SP - 272
EP - 285
BT - Springer Series in Chemical Physics
ER -