Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature

Kohei Endo, Takahiro Ohkubo, Munenao Hirokami, Takanori Shibata

    Research output: Contribution to journal › Article

    126 Citations (Scopus)

    Abstract

    The palladium-catalyzed Suzuki-Miyaura cross-coupling on a multisubstituted sp3-carbon in 1,1-diborylalkanes was achieved at room temperature. The generation of a monoborate intermediate by virtue of the adjacent B atom could result in the chemoselective coupling reaction under ambient conditions.

    Original languageEnglish
    Pages (from-to)11033-11035
    Number of pages3
    JournalJournal of the American Chemical Society
    Volume132
    Issue number32
    DOIs
    Publication statusPublished - 2010 Aug 18

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    Palladium
    Carbon
    Atoms
    Temperature

    ASJC Scopus subject areas

    • Chemistry(all)
    • Catalysis
    • Biochemistry
    • Colloid and Surface Chemistry

    Cite this

    Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature. / Endo, Kohei; Ohkubo, Takahiro; Hirokami, Munenao; Shibata, Takanori.

    In: Journal of the American Chemical Society, Vol. 132, No. 32, 18.08.2010, p. 11033-11035.

    Research output: Contribution to journal › Article

    Endo, K, Ohkubo, T, Hirokami, M & Shibata, T 2010, 'Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature', Journal of the American Chemical Society, vol. 132, no. 32, pp. 11033-11035. https://doi.org/10.1021/ja105176v
    Endo K, Ohkubo T, Hirokami M, Shibata T. Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature. Journal of the American Chemical Society. 2010 Aug 18;132(32):11033-11035. https://doi.org/10.1021/ja105176v
    Endo, Kohei ; Ohkubo, Takahiro ; Hirokami, Munenao ; Shibata, Takanori. / Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature. In: Journal of the American Chemical Society. 2010 ; Vol. 132, No. 32. pp. 11033-11035.
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