Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature

Kohei Endo; Takahiro Ohkubo; Munenao Hirokami; Takanori Shibata

doi:10.1021/ja105176v

Chemoselective and regiospecific suzuki coupling on a multisubstituted sp³-Carbon in 1,1-diborylalkanes at room temperature

Kohei Endo, Takahiro Ohkubo, Munenao Hirokami, Takanori Shibata

School of Advanced Science and Engineering

Research output: Contribution to journal › Article › peer-review

140 Citations (Scopus)

Abstract

The palladium-catalyzed Suzuki-Miyaura cross-coupling on a multisubstituted sp³-carbon in 1,1-diborylalkanes was achieved at room temperature. The generation of a monoborate intermediate by virtue of the adjacent B atom could result in the chemoselective coupling reaction under ambient conditions.

Original language	English
Pages (from-to)	11033-11035
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	132
Issue number	32
DOIs	https://doi.org/10.1021/ja105176v
Publication status	Published - 2010 Aug 18

ASJC Scopus subject areas

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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abstract = "The palladium-catalyzed Suzuki-Miyaura cross-coupling on a multisubstituted sp3-carbon in 1,1-diborylalkanes was achieved at room temperature. The generation of a monoborate intermediate by virtue of the adjacent B atom could result in the chemoselective coupling reaction under ambient conditions.",

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AU - Hirokami, Munenao

AU - Shibata, Takanori

PY - 2010/8/18

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N2 - The palladium-catalyzed Suzuki-Miyaura cross-coupling on a multisubstituted sp3-carbon in 1,1-diborylalkanes was achieved at room temperature. The generation of a monoborate intermediate by virtue of the adjacent B atom could result in the chemoselective coupling reaction under ambient conditions.

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Chemoselective and regiospecific suzuki coupling on a multisubstituted sp³-Carbon in 1,1-diborylalkanes at room temperature

Abstract

ASJC Scopus subject areas

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