Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature

Kohei Endo, Takahiro Ohkubo, Munenao Hirokami, Takanori Shibata

    Research output: Contribution to journalArticle

    121 Citations (Scopus)

    Abstract

    The palladium-catalyzed Suzuki-Miyaura cross-coupling on a multisubstituted sp3-carbon in 1,1-diborylalkanes was achieved at room temperature. The generation of a monoborate intermediate by virtue of the adjacent B atom could result in the chemoselective coupling reaction under ambient conditions.

    Original languageEnglish
    Pages (from-to)11033-11035
    Number of pages3
    JournalJournal of the American Chemical Society
    Volume132
    Issue number32
    DOIs
    Publication statusPublished - 2010 Aug 18

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    Palladium
    Carbon
    Atoms
    Temperature

    ASJC Scopus subject areas

    • Chemistry(all)
    • Catalysis
    • Biochemistry
    • Colloid and Surface Chemistry

    Cite this

    Chemoselective and regiospecific suzuki coupling on a multisubstituted sp3-Carbon in 1,1-diborylalkanes at room temperature. / Endo, Kohei; Ohkubo, Takahiro; Hirokami, Munenao; Shibata, Takanori.

    In: Journal of the American Chemical Society, Vol. 132, No. 32, 18.08.2010, p. 11033-11035.

    Research output: Contribution to journalArticle

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