Abstract
The chemoselective Pd-catalyzed Suzuki-Miyaura cross-coupling reaction using a diborylmethane is reported. The use of an equimolar amount of base with a diborylmethane realized chemoselective coupling for the synthesis of various benzylboronate derivatives. Sterically hindered aryl bromides can give products in moderate to excellent yields.
| Original language | English |
|---|---|
| Pages (from-to) | 3368-3371 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 13 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - 2011 Jul 1 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Cite this
Endo, K., Ohkubo, T., & Shibata, T. (2011). Chemoselective Suzuki coupling of diborylmethane for facile synthesis of benzylboronates. Organic Letters, 13(13), 3368-3371. https://doi.org/10.1021/ol201115k