TY - JOUR
T1 - Chiral secondary alcohol-induced asymmetric autocatalysis
T2 - correlation between the absolute configuration of the chiral initiators and the product
AU - Shibata, Takanori
AU - Iwahashi, Kimiko
AU - Kawasaki, Tsuneomi
AU - Soai, Kenso
N1 - Funding Information:
This research was supported by a Grant-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan.
PY - 2007/8/9
Y1 - 2007/8/9
N2 - In the presence of various chiral secondary alcohols as chiral initiators, an enantioselective alkylation of a pyrimidine-5-carbaldehyde using diisopropylzinc was examined: a pyrimidyl alkanol was obtained in high yield and enantiomeric excess. The correlation between the absolute configuration of the chiral secondary alcohols and the pyrimidyl alkanol is discussed.
AB - In the presence of various chiral secondary alcohols as chiral initiators, an enantioselective alkylation of a pyrimidine-5-carbaldehyde using diisopropylzinc was examined: a pyrimidyl alkanol was obtained in high yield and enantiomeric excess. The correlation between the absolute configuration of the chiral secondary alcohols and the pyrimidyl alkanol is discussed.
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U2 - 10.1016/j.tetasy.2007.07.030
DO - 10.1016/j.tetasy.2007.07.030
M3 - Article
AN - SCOPUS:34548417133
VL - 18
SP - 1759
EP - 1762
JO - Tetrahedron Asymmetry
JF - Tetrahedron Asymmetry
SN - 0957-4166
IS - 15
ER -