Chronic Effects of Voluntary Exercise on Srbc-Induced Host Defense Reactions in Rats

Katsuhiko Suzuki, Kazuhiko Machida, Mieko Kariya, Keiko Arikura, Yasuhiro Ina, Kazumasa Tsukamoto

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A study was conducted to evaluate the chronic effects of regular physical activity on nonspecific and specific immune responses. Male Fischer rats (SPF) exercised voluntarily on running wheels for 4 months, and were then injected intraperitoneally with sheep red blood cells (SRBC), followed by measurement of the host defense functions at -2 d, 3 h, 24 h and 4 d of antigen stimulation. The following results were obtained.

Original languageEnglish
Pages (from-to)145-154
Number of pages10
JournalJapanese Journal of Physical Fitness and Sports Medicine
Issue number2
Publication statusPublished - 1993



  • free radicals
  • immunoglobulins
  • neutrophils
  • rats
  • voluntary exercise

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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