Circulating leptin levels are associated with physical activity or physical fitness in Japanese

Nobuyuki Miyatake*, Haruka Murakami, Ryoko Kawakami, Izumi Tabata, Motohiko Miyachi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Objective: The aim of this study was to evaluate the link between circulating leptin levels and physical activity and/or physical fitness in apparently healthy Japanese.

Methods: A total of 85 men and 111 women who were not taking any medication were enrolled in this cross-sectional study. Circulating leptin levels, physical activity measured by tri-axial accelerometers and peak oxygen uptake were evaluated. We also assessed anthropometric data, blood pressure, blood examinations and energy intake.

Results: Circulating leptin levels were 3.2 ± 2.3 ng/mL in men and 5.9 ± 3.8 ng/mL in women. Circulating leptin levels were significantly and positively correlated with body weight, body mass index, abdominal circumference, insulin and the homeostasis model assessment index, and significantly and negatively correlated with peak oxygen uptake in both sexes. Stepwise multiple regression showed that peak oxygen uptake in men and physical activity evaluated by (Formula presented.) in women were determinant factors for circulating leptin levels after adjusting for confounding factors.

Original languageEnglish
Pages (from-to)362-366
Number of pages5
JournalEnvironmental Health and Preventive Medicine
Issue number5
Publication statusPublished - 2014 Sep 18
Externally publishedYes


  • Japanese
  • Leptin
  • Peak oxygen uptake
  • Physical activity
  • Tri-axial accelerometer

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health


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