Abstract
The photon radiosurgery system is a miniature X-ray generator that can be placed stereotactically and intraoperatively into intracranial tumors to deliver a single fraction of high-dose interstitial irradiation. This battery-powered device produces low energy X-ray photons in a spherical and symmetrical pattern at the probe tip. Dose rates of up to 200 cGy/Mim are possible, allowing for the administration of 15 Gy to a lesion 3 cm in diameter in less than 1 hr. Background exposure is minimal, and no special shielding of the patient or health care personnel is required. Thirty-nine patients with brain tumor were treated in this method. There were no adverse effects. During the follow-up period of 1-30 months, 3 cases with 5 metastatic brain tumors died about 8 months after this treatment. Five recurrent cases of 21 malignant gliomas died about 4 months after treatment. Interstitial radiotherapy using photon the radiosurgery system promises to be a useful treatment for brain tumors.
| Original language | English |
|---|---|
| Pages (from-to) | 1348-1351 |
| Number of pages | 4 |
| Journal | Gan to kagaku ryoho. Cancer & chemotherapy |
| Volume | 25 |
| Issue number | 9 |
| Publication status | Published - 1998 Jul |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cancer Research
- Pharmacology
Cite this
Clinical evaluation of intraoperative radiotherapy using photon radiosurgery system for brain tumors. / Kubo, O.; Muragaki, Y.; Iseki, Hiroshi; Takakura, K.
In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 25, No. 9, 07.1998, p. 1348-1351.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical evaluation of intraoperative radiotherapy using photon radiosurgery system for brain tumors
AU - Kubo, O.
AU - Muragaki, Y.
AU - Iseki, Hiroshi
AU - Takakura, K.
PY - 1998/7
Y1 - 1998/7
N2 - The photon radiosurgery system is a miniature X-ray generator that can be placed stereotactically and intraoperatively into intracranial tumors to deliver a single fraction of high-dose interstitial irradiation. This battery-powered device produces low energy X-ray photons in a spherical and symmetrical pattern at the probe tip. Dose rates of up to 200 cGy/Mim are possible, allowing for the administration of 15 Gy to a lesion 3 cm in diameter in less than 1 hr. Background exposure is minimal, and no special shielding of the patient or health care personnel is required. Thirty-nine patients with brain tumor were treated in this method. There were no adverse effects. During the follow-up period of 1-30 months, 3 cases with 5 metastatic brain tumors died about 8 months after this treatment. Five recurrent cases of 21 malignant gliomas died about 4 months after treatment. Interstitial radiotherapy using photon the radiosurgery system promises to be a useful treatment for brain tumors.
AB - The photon radiosurgery system is a miniature X-ray generator that can be placed stereotactically and intraoperatively into intracranial tumors to deliver a single fraction of high-dose interstitial irradiation. This battery-powered device produces low energy X-ray photons in a spherical and symmetrical pattern at the probe tip. Dose rates of up to 200 cGy/Mim are possible, allowing for the administration of 15 Gy to a lesion 3 cm in diameter in less than 1 hr. Background exposure is minimal, and no special shielding of the patient or health care personnel is required. Thirty-nine patients with brain tumor were treated in this method. There were no adverse effects. During the follow-up period of 1-30 months, 3 cases with 5 metastatic brain tumors died about 8 months after this treatment. Five recurrent cases of 21 malignant gliomas died about 4 months after treatment. Interstitial radiotherapy using photon the radiosurgery system promises to be a useful treatment for brain tumors.
UR - http://www.scopus.com/inward/record.url?scp=0032113997&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032113997&partnerID=8YFLogxK
M3 - Article
C2 - 9703825
AN - SCOPUS:0032113997
VL - 25
SP - 1348
EP - 1351
JO - Gan to kagaku ryoho. Cancer & chemotherapy
JF - Gan to kagaku ryoho. Cancer & chemotherapy
SN - 0385-0684
IS - 9
ER -