Cl- sensitive biosensor used electrolyte-solution-gate diamond FETs

Kwang Soup Song, Toshikatsu Sakai, Hirofumi Kanazawa, Yuta Araki, Hitoshi Umezawa, Minoru Tachiki, Hiroshi Kawarada

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

We have investigated the electrolyte-solution-gate field effect transisitors (SGFETs) used hydrogen terminated (H-terminated) or partially oxygen terminated (O-terminated) polycrystalline diamond surface in the Cl - and Br- ionic solutions. The H-terminated channel SGFETs are insensitive to pH values in electrolyte solutions. The threshold voltages of the diamond SGFETs shift according to the density of Cl- and Br- ions about 30 mV/decade. One of the attractive biomedical applications for the Cl- sensitive SGFETs is the detection of chloride density in blood or in sweat especially in the case of cystic fibrosis. The sensitivities of Cl- and Br- ions have been lost on the partially O-terminated diamond surface. These phenomena can be explained by the polarity of surface change on the H-terminated and the O-terminated surface.

Original languageEnglish
Pages (from-to)137-140
Number of pages4
JournalBiosensors and Bioelectronics
Volume19
Issue number2
DOIs
Publication statusPublished - 2003 Nov 15

Keywords

  • Cl and Br ionic solution
  • Cystic fibrosis
  • Hydrogen-terminated diamond
  • Oxygen-terminated diamond
  • Threshold voltage

ASJC Scopus subject areas

  • Biotechnology
  • Biophysics
  • Biomedical Engineering
  • Electrochemistry

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