Cognitive dysfunctions after recovery from major depressive episodes

Tetsuya Yamamoto, Hironori Shimada

    Research output: Contribution to journalArticle

    6 Citations (Scopus)

    Abstract

    Although recent studies have indicated that cognitive dysfunctions may persist after recovery from a major depressive episode (MDE), the claim remains controversial. To clarify this clinically important issue, we investigated the cognitive functions of people who had experienced one or more MDE, after controlling for several confounding variables: differences in (a) medications, (b) age ranges, and (c) disorder characteristics. Neuropsychological tests for memory, attention, and executive function were employed to compare 12 recovered depressed participants who had fully met the criteria for MDE to 30 participants who had partially met the criteria or had not met them at all. The recovered depressed participants were impaired on tasks of verbal learning and memory and selective or divided attention in contrast to others. After an alpha correction was applied, the deficits in divided attention remained significant. These cognitive shortfalls also distinguished people who had experienced an MDE from those who had partially experienced them or had not experienced them at all. We suggest that the experience of an MDE may have a persistent negative influence on cognitive functions, particularly on their higher levels, such as divided attention.

    Original languageEnglish
    Pages (from-to)183-191
    Number of pages9
    JournalApplied Neuropsychology
    Volume19
    Issue number3
    DOIs
    Publication statusPublished - 2012 Jul 1

    Fingerprint

    Cognition
    Verbal Learning
    Confounding Factors (Epidemiology)
    Neuropsychological Tests
    Executive Function
    Cognitive Dysfunction
    Recovery
    Divided Attention
    Cognitive Function
    Selective Attention
    Verbal Memory
    Learning and Memory
    Medication

    Keywords

    • attention
    • cognitive function
    • depression
    • neuropsychological test
    • recovery

    ASJC Scopus subject areas

    • Neuropsychology and Physiological Psychology
    • Developmental and Educational Psychology
    • Arts and Humanities (miscellaneous)

    Cite this

    Cognitive dysfunctions after recovery from major depressive episodes. / Yamamoto, Tetsuya; Shimada, Hironori.

    In: Applied Neuropsychology, Vol. 19, No. 3, 01.07.2012, p. 183-191.

    Research output: Contribution to journalArticle

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