Abstract
We fabricated micro flow channel based on the collagen tunnel for in vitro BBB blood capirary model using collagen gel tunnel, PDMS and infrared laser. This flow channel system can add the influence of shear stress to EC and evaluate the permeability by continuous microfluidic flow during cultivation. This system is expected to become a novel tool for emulating in vivo permeability of drug candidates available only in small quantities.
| Original language | English |
|---|---|
| Title of host publication | Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC |
| Pages | 510-511 |
| Number of pages | 2 |
| DOIs | |
| Publication status | Published - 2007 Dec 1 |
| Externally published | Yes |
| Event | s20th International Microprocesses and Nanotechnology Conference, MNC 2007 - Kyoto, Japan Duration: 2007 Nov 5 → 2007 Nov 8 |
Publication series
| Name | Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC |
|---|
Other
| Other | s20th International Microprocesses and Nanotechnology Conference, MNC 2007 |
|---|---|
| Country | Japan |
| City | Kyoto |
| Period | 07/11/5 → 07/11/8 |
ASJC Scopus subject areas
- Hardware and Architecture
- Electrical and Electronic Engineering
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Cite this
Shibata, K., Terazono, H., Hattori, A., & Yasuda, K. (2007). Collagen micro flow channel for in vitro Blood-Brain Barrier model. In Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC (pp. 510-511). [4456328] (Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC). https://doi.org/10.1109/IMNC.2007.4456328