Abstract
We fabricated micro flow channel based on the collagen tunnel for in vitro BBB blood capirary model using collagen gel tunnel, PDMS and infrared laser. This flow channel system can add the influence of shear stress to EC and evaluate the permeability by continuous microfluidic flow during cultivation. This system is expected to become a novel tool for emulating in vivo permeability of drug candidates available only in small quantities.
| Original language | English |
|---|---|
| Title of host publication | Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC |
| Pages | 510-511 |
| Number of pages | 2 |
| DOIs | |
| Publication status | Published - 2007 |
| Externally published | Yes |
| Event | s20th International Microprocesses and Nanotechnology Conference, MNC 2007 - Kyoto, Japan Duration: 2007 Nov 5 → 2007 Nov 8 |
Other
| Other | s20th International Microprocesses and Nanotechnology Conference, MNC 2007 |
|---|---|
| Country | Japan |
| City | Kyoto |
| Period | 07/11/5 → 07/11/8 |
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ASJC Scopus subject areas
- Hardware and Architecture
- Electrical and Electronic Engineering
Cite this
Collagen micro flow channel for in vitro Blood-Brain Barrier model. / Shibata, K.; Terazono, H.; Hattori, Akihiro; Yasuda, Kenji.
Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. p. 510-511 4456328.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Collagen micro flow channel for in vitro Blood-Brain Barrier model
AU - Shibata, K.
AU - Terazono, H.
AU - Hattori, Akihiro
AU - Yasuda, Kenji
PY - 2007
Y1 - 2007
N2 - We fabricated micro flow channel based on the collagen tunnel for in vitro BBB blood capirary model using collagen gel tunnel, PDMS and infrared laser. This flow channel system can add the influence of shear stress to EC and evaluate the permeability by continuous microfluidic flow during cultivation. This system is expected to become a novel tool for emulating in vivo permeability of drug candidates available only in small quantities.
AB - We fabricated micro flow channel based on the collagen tunnel for in vitro BBB blood capirary model using collagen gel tunnel, PDMS and infrared laser. This flow channel system can add the influence of shear stress to EC and evaluate the permeability by continuous microfluidic flow during cultivation. This system is expected to become a novel tool for emulating in vivo permeability of drug candidates available only in small quantities.
UR - http://www.scopus.com/inward/record.url?scp=47349089440&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=47349089440&partnerID=8YFLogxK
U2 - 10.1109/IMNC.2007.4456328
DO - 10.1109/IMNC.2007.4456328
M3 - Conference contribution
AN - SCOPUS:47349089440
SN - 4990247248
SN - 9784990247249
SP - 510
EP - 511
BT - Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC
ER -