Collagen micro flow channel for in vitro Blood-Brain Barrier model

K. Shibata; H. Terazono; Akihiro Hattori; Kenji Yasuda

doi:10.1109/IMNC.2007.4456328

Collagen micro flow channel for in vitro Blood-Brain Barrier model

K. Shibata, H. Terazono, Akihiro Hattori, Kenji Yasuda

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We fabricated micro flow channel based on the collagen tunnel for in vitro BBB blood capirary model using collagen gel tunnel, PDMS and infrared laser. This flow channel system can add the influence of shear stress to EC and evaluate the permeability by continuous microfluidic flow during cultivation. This system is expected to become a novel tool for emulating in vivo permeability of drug candidates available only in small quantities.

Original language	English
Title of host publication	Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC
Pages	510-511
Number of pages	2
DOIs	https://doi.org/10.1109/IMNC.2007.4456328
Publication status	Published - 2007
Externally published	Yes
Event	s20th International Microprocesses and Nanotechnology Conference, MNC 2007 - Kyoto, Japan Duration: 2007 Nov 5 → 2007 Nov 8

Other

Other	s20th International Microprocesses and Nanotechnology Conference, MNC 2007
Country	Japan
City	Kyoto
Period	07/11/5 → 07/11/8

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ASJC Scopus subject areas

Hardware and Architecture
Electrical and Electronic Engineering

Cite this

Shibata, K., Terazono, H., Hattori, A., & Yasuda, K. (2007). Collagen micro flow channel for in vitro Blood-Brain Barrier model. In Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC (pp. 510-511). [4456328] https://doi.org/10.1109/IMNC.2007.4456328

Collagen micro flow channel for in vitro Blood-Brain Barrier model. / Shibata, K.; Terazono, H.; Hattori, Akihiro ; Yasuda, Kenji.

Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC. 2007. p. 510-511 4456328.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Shibata, K, Terazono, H, Hattori, A & Yasuda, K 2007, Collagen micro flow channel for in vitro Blood-Brain Barrier model. in Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC., 4456328, pp. 510-511, s20th International Microprocesses and Nanotechnology Conference, MNC 2007, Kyoto, Japan, 07/11/5. https://doi.org/10.1109/IMNC.2007.4456328

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Access to Document

10.1109/IMNC.2007.4456328