Collagen micro flow channel for in vitro Blood-Brain Barrier model

K. Shibata, H. Terazono, Akihiro Hattori, Kenji Yasuda

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We fabricated micro flow channel based on the collagen tunnel for in vitro BBB blood capirary model using collagen gel tunnel, PDMS and infrared laser. This flow channel system can add the influence of shear stress to EC and evaluate the permeability by continuous microfluidic flow during cultivation. This system is expected to become a novel tool for emulating in vivo permeability of drug candidates available only in small quantities.

Original languageEnglish
Title of host publicationDigest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC
Pages510-511
Number of pages2
DOIs
Publication statusPublished - 2007
Externally publishedYes
Events20th International Microprocesses and Nanotechnology Conference, MNC 2007 - Kyoto, Japan
Duration: 2007 Nov 52007 Nov 8

Other

Others20th International Microprocesses and Nanotechnology Conference, MNC 2007
CountryJapan
CityKyoto
Period07/11/507/11/8

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ASJC Scopus subject areas

  • Hardware and Architecture
  • Electrical and Electronic Engineering

Cite this

Shibata, K., Terazono, H., Hattori, A., & Yasuda, K. (2007). Collagen micro flow channel for in vitro Blood-Brain Barrier model. In Digest of Papers - Microprocesses and Nanotechnology 2007; 20th International Microprocesses and Nanotechnology Conference, MNC (pp. 510-511). [4456328] https://doi.org/10.1109/IMNC.2007.4456328