Comparing accuracy of cerebral aneurysm size measurements from three routine investigations

Computed tomography, magnetic resonance imaging, and digital subtraction angiography

Hiroyuki Takao, Yuichi Murayama, Toshihiro Ishibashi, Takayuki Saguchi, Masaki Ebara, Hideki Arakawa, Koreaki Irie, Kiyotaka Iwasaki, Mitsuo Umezu, Toshiaki Abe

    Research output: Contribution to journalArticle

    11 Citations (Scopus)

    Abstract

    Modern imaging technologies, such as computed tomography (CT) angiography, magnetic resonance (MR) angiography, and digital subtraction (DS) angiography are widely used for pretreatment evaluation of cerebral aneurysms, but the relative accuracies of these modalities are unclear. This study compared the measurements of aneurysm neck and dome height and width on CT angiography, time-of-flight (TOF)-MR angiography, and DS angiography using a three-dimensional workstation. An elastic model of a side-wall aneurysm was connected to an artificial heart pulsatile circuit system. The aneurysm model was prepared using a silicone membrane of 0.6-mm thickness under normal physiological circulation parameters. Using this aneurysm model, three-dimensional TOF-MR angiography, contrast-enhanced CT angiography, and DS angiography were performed. Source images were post-processed on a dedicated workstation to calculate the aneurysm size. DS angiography measurements were found to be the most accurate. In contrast, aneurysm neck sizes measured on CT angiography were significantly wider than actual values (p < 0.05) and aneurysm heights measured using TOF-MR an-giography were significantly lower than actual values (p < 0.01). In this in-vitro model, at least one aneurysm dimension measured with CT angiography and with TOF-MR angiography differed significantly from actual values. Aneurysm neck width markedly affects therapeutic planning, as a wide neck requires craniotomy or endovascular treatment using an adjunctive device, so inaccuracies should be considered when aneurysm treatment is planned using modern methods of visualization.

    Original languageEnglish
    Pages (from-to)893-899
    Number of pages7
    JournalNeurologia Medico-Chirurgica
    Volume50
    Issue number10
    DOIs
    Publication statusPublished - 2010

    Fingerprint

    Digital Subtraction Angiography
    Intracranial Aneurysm
    Aneurysm
    Tomography
    Magnetic Resonance Imaging
    Magnetic Resonance Angiography
    Artificial Heart
    Craniotomy
    Silicones
    Neck
    Magnetic Resonance Spectroscopy
    Computed Tomography Angiography
    Technology
    Equipment and Supplies

    Keywords

    • Cerebral aneurysm
    • Computed tomography
    • Digital subtraction angiography
    • Magnetic resonance imaging
    • Size measurement

    ASJC Scopus subject areas

    • Clinical Neurology
    • Surgery

    Cite this

    Comparing accuracy of cerebral aneurysm size measurements from three routine investigations : Computed tomography, magnetic resonance imaging, and digital subtraction angiography. / Takao, Hiroyuki; Murayama, Yuichi; Ishibashi, Toshihiro; Saguchi, Takayuki; Ebara, Masaki; Arakawa, Hideki; Irie, Koreaki; Iwasaki, Kiyotaka; Umezu, Mitsuo; Abe, Toshiaki.

    In: Neurologia Medico-Chirurgica, Vol. 50, No. 10, 2010, p. 893-899.

    Research output: Contribution to journalArticle

    Takao, Hiroyuki ; Murayama, Yuichi ; Ishibashi, Toshihiro ; Saguchi, Takayuki ; Ebara, Masaki ; Arakawa, Hideki ; Irie, Koreaki ; Iwasaki, Kiyotaka ; Umezu, Mitsuo ; Abe, Toshiaki. / Comparing accuracy of cerebral aneurysm size measurements from three routine investigations : Computed tomography, magnetic resonance imaging, and digital subtraction angiography. In: Neurologia Medico-Chirurgica. 2010 ; Vol. 50, No. 10. pp. 893-899.
    @article{164fb852d19746b79ce173b145c4ec53,
    title = "Comparing accuracy of cerebral aneurysm size measurements from three routine investigations: Computed tomography, magnetic resonance imaging, and digital subtraction angiography",
    abstract = "Modern imaging technologies, such as computed tomography (CT) angiography, magnetic resonance (MR) angiography, and digital subtraction (DS) angiography are widely used for pretreatment evaluation of cerebral aneurysms, but the relative accuracies of these modalities are unclear. This study compared the measurements of aneurysm neck and dome height and width on CT angiography, time-of-flight (TOF)-MR angiography, and DS angiography using a three-dimensional workstation. An elastic model of a side-wall aneurysm was connected to an artificial heart pulsatile circuit system. The aneurysm model was prepared using a silicone membrane of 0.6-mm thickness under normal physiological circulation parameters. Using this aneurysm model, three-dimensional TOF-MR angiography, contrast-enhanced CT angiography, and DS angiography were performed. Source images were post-processed on a dedicated workstation to calculate the aneurysm size. DS angiography measurements were found to be the most accurate. In contrast, aneurysm neck sizes measured on CT angiography were significantly wider than actual values (p < 0.05) and aneurysm heights measured using TOF-MR an-giography were significantly lower than actual values (p < 0.01). In this in-vitro model, at least one aneurysm dimension measured with CT angiography and with TOF-MR angiography differed significantly from actual values. Aneurysm neck width markedly affects therapeutic planning, as a wide neck requires craniotomy or endovascular treatment using an adjunctive device, so inaccuracies should be considered when aneurysm treatment is planned using modern methods of visualization.",
    keywords = "Cerebral aneurysm, Computed tomography, Digital subtraction angiography, Magnetic resonance imaging, Size measurement",
    author = "Hiroyuki Takao and Yuichi Murayama and Toshihiro Ishibashi and Takayuki Saguchi and Masaki Ebara and Hideki Arakawa and Koreaki Irie and Kiyotaka Iwasaki and Mitsuo Umezu and Toshiaki Abe",
    year = "2010",
    doi = "10.2176/nmc.50.893",
    language = "English",
    volume = "50",
    pages = "893--899",
    journal = "Neurologia Medico-Chirurgica",
    issn = "0387-2572",
    publisher = "Japan Neurosurgical Society",
    number = "10",

    }

    TY - JOUR

    T1 - Comparing accuracy of cerebral aneurysm size measurements from three routine investigations

    T2 - Computed tomography, magnetic resonance imaging, and digital subtraction angiography

    AU - Takao, Hiroyuki

    AU - Murayama, Yuichi

    AU - Ishibashi, Toshihiro

    AU - Saguchi, Takayuki

    AU - Ebara, Masaki

    AU - Arakawa, Hideki

    AU - Irie, Koreaki

    AU - Iwasaki, Kiyotaka

    AU - Umezu, Mitsuo

    AU - Abe, Toshiaki

    PY - 2010

    Y1 - 2010

    N2 - Modern imaging technologies, such as computed tomography (CT) angiography, magnetic resonance (MR) angiography, and digital subtraction (DS) angiography are widely used for pretreatment evaluation of cerebral aneurysms, but the relative accuracies of these modalities are unclear. This study compared the measurements of aneurysm neck and dome height and width on CT angiography, time-of-flight (TOF)-MR angiography, and DS angiography using a three-dimensional workstation. An elastic model of a side-wall aneurysm was connected to an artificial heart pulsatile circuit system. The aneurysm model was prepared using a silicone membrane of 0.6-mm thickness under normal physiological circulation parameters. Using this aneurysm model, three-dimensional TOF-MR angiography, contrast-enhanced CT angiography, and DS angiography were performed. Source images were post-processed on a dedicated workstation to calculate the aneurysm size. DS angiography measurements were found to be the most accurate. In contrast, aneurysm neck sizes measured on CT angiography were significantly wider than actual values (p < 0.05) and aneurysm heights measured using TOF-MR an-giography were significantly lower than actual values (p < 0.01). In this in-vitro model, at least one aneurysm dimension measured with CT angiography and with TOF-MR angiography differed significantly from actual values. Aneurysm neck width markedly affects therapeutic planning, as a wide neck requires craniotomy or endovascular treatment using an adjunctive device, so inaccuracies should be considered when aneurysm treatment is planned using modern methods of visualization.

    AB - Modern imaging technologies, such as computed tomography (CT) angiography, magnetic resonance (MR) angiography, and digital subtraction (DS) angiography are widely used for pretreatment evaluation of cerebral aneurysms, but the relative accuracies of these modalities are unclear. This study compared the measurements of aneurysm neck and dome height and width on CT angiography, time-of-flight (TOF)-MR angiography, and DS angiography using a three-dimensional workstation. An elastic model of a side-wall aneurysm was connected to an artificial heart pulsatile circuit system. The aneurysm model was prepared using a silicone membrane of 0.6-mm thickness under normal physiological circulation parameters. Using this aneurysm model, three-dimensional TOF-MR angiography, contrast-enhanced CT angiography, and DS angiography were performed. Source images were post-processed on a dedicated workstation to calculate the aneurysm size. DS angiography measurements were found to be the most accurate. In contrast, aneurysm neck sizes measured on CT angiography were significantly wider than actual values (p < 0.05) and aneurysm heights measured using TOF-MR an-giography were significantly lower than actual values (p < 0.01). In this in-vitro model, at least one aneurysm dimension measured with CT angiography and with TOF-MR angiography differed significantly from actual values. Aneurysm neck width markedly affects therapeutic planning, as a wide neck requires craniotomy or endovascular treatment using an adjunctive device, so inaccuracies should be considered when aneurysm treatment is planned using modern methods of visualization.

    KW - Cerebral aneurysm

    KW - Computed tomography

    KW - Digital subtraction angiography

    KW - Magnetic resonance imaging

    KW - Size measurement

    UR - http://www.scopus.com/inward/record.url?scp=78149232921&partnerID=8YFLogxK

    UR - http://www.scopus.com/inward/citedby.url?scp=78149232921&partnerID=8YFLogxK

    U2 - 10.2176/nmc.50.893

    DO - 10.2176/nmc.50.893

    M3 - Article

    VL - 50

    SP - 893

    EP - 899

    JO - Neurologia Medico-Chirurgica

    JF - Neurologia Medico-Chirurgica

    SN - 0387-2572

    IS - 10

    ER -