Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral

T. Thiebault, M. Boussafir, L. Le Forestier, C. Le Milbeau, L. Monnin, Regis Guegan

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The removal of a Pharmaceutically Active Compound (PhAC) pool using a well referenced clay mineral from Wyoming (SWy-2) as a geosorbent was studied for a better understanding of the environmental fate. As expected, the selected material shows its particular adsorption properties to PhAC under different experimental conditions with two main features depending on the chemical nature of the emerging micro-pollutants. Cationic PhACs, for which the driving force for their adsorption results from electrostatic interaction via the exchange with the inorganic cations of the clay mineral, are almost completely removed for all studied experimental conditions where it appears that the S/L ratio plays a minor role and the only one limitation for their removal is the cation exchange capacity of the adsorbent. In contrast, anionic and neutral PhACs are adsorbed to the clay mineral surface (silanol groups on the sheet edges, inorganic cations...) through other interactional mechanisms involving ion-dipole, van der Waals interaction, leading to a competition of all organic molecules where their chemical nature (electric charge, hydrophobicity) may also play a role in their adsorption. While the adsorption of ketoprofen, naproxen, diclofenac and salicylic acid anionic PhACs slightly increases with the increase of the S/L ratio, the removal of the neutral and the other anionic PhACs (gemfibrozil and ibuprofen) seems to be independent of that ratio and is particularly enhanced. The efficiency of the removal for a global pool of PhACs even in low S/L ratio stresses the control of the selected natural minerals on the dynamics of PhACs in the environment.

Original languageEnglish
Pages (from-to)65257-65265
Number of pages9
JournalRSC Advances
Volume6
Issue number69
DOIs
Publication statusPublished - 2016 Jan 1
Externally publishedYes

Fingerprint

Clay minerals
Drug products
Cations
Adsorption
Positive ions
Pharmaceutical Preparations
Ion exchange
Gemfibrozil
Salicylic acid
Ketoprofen
Naproxen
Electric charge
Salicylic Acid
Diclofenac
Ibuprofen
Hydrophobicity
Coulomb interactions
Adsorbents
Minerals
Ions

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Thiebault, T., Boussafir, M., Le Forestier, L., Le Milbeau, C., Monnin, L., & Guegan, R. (2016). Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral. RSC Advances, 6(69), 65257-65265. https://doi.org/10.1039/c6ra10655b

Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral. / Thiebault, T.; Boussafir, M.; Le Forestier, L.; Le Milbeau, C.; Monnin, L.; Guegan, Regis.

In: RSC Advances, Vol. 6, No. 69, 01.01.2016, p. 65257-65265.

Research output: Contribution to journalArticle

Thiebault, T, Boussafir, M, Le Forestier, L, Le Milbeau, C, Monnin, L & Guegan, R 2016, 'Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral', RSC Advances, vol. 6, no. 69, pp. 65257-65265. https://doi.org/10.1039/c6ra10655b
Thiebault T, Boussafir M, Le Forestier L, Le Milbeau C, Monnin L, Guegan R. Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral. RSC Advances. 2016 Jan 1;6(69):65257-65265. https://doi.org/10.1039/c6ra10655b
Thiebault, T. ; Boussafir, M. ; Le Forestier, L. ; Le Milbeau, C. ; Monnin, L. ; Guegan, Regis. / Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral. In: RSC Advances. 2016 ; Vol. 6, No. 69. pp. 65257-65265.
@article{71604e583e3141c9a90ee1ba3c40134d,
title = "Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral",
abstract = "The removal of a Pharmaceutically Active Compound (PhAC) pool using a well referenced clay mineral from Wyoming (SWy-2) as a geosorbent was studied for a better understanding of the environmental fate. As expected, the selected material shows its particular adsorption properties to PhAC under different experimental conditions with two main features depending on the chemical nature of the emerging micro-pollutants. Cationic PhACs, for which the driving force for their adsorption results from electrostatic interaction via the exchange with the inorganic cations of the clay mineral, are almost completely removed for all studied experimental conditions where it appears that the S/L ratio plays a minor role and the only one limitation for their removal is the cation exchange capacity of the adsorbent. In contrast, anionic and neutral PhACs are adsorbed to the clay mineral surface (silanol groups on the sheet edges, inorganic cations...) through other interactional mechanisms involving ion-dipole, van der Waals interaction, leading to a competition of all organic molecules where their chemical nature (electric charge, hydrophobicity) may also play a role in their adsorption. While the adsorption of ketoprofen, naproxen, diclofenac and salicylic acid anionic PhACs slightly increases with the increase of the S/L ratio, the removal of the neutral and the other anionic PhACs (gemfibrozil and ibuprofen) seems to be independent of that ratio and is particularly enhanced. The efficiency of the removal for a global pool of PhACs even in low S/L ratio stresses the control of the selected natural minerals on the dynamics of PhACs in the environment.",
author = "T. Thiebault and M. Boussafir and {Le Forestier}, L. and {Le Milbeau}, C. and L. Monnin and Regis Guegan",
year = "2016",
month = "1",
day = "1",
doi = "10.1039/c6ra10655b",
language = "English",
volume = "6",
pages = "65257--65265",
journal = "RSC Advances",
issn = "2046-2069",
publisher = "Royal Society of Chemistry",
number = "69",

}

TY - JOUR

T1 - Competitive adsorption of a pool of pharmaceuticals onto a raw clay mineral

AU - Thiebault, T.

AU - Boussafir, M.

AU - Le Forestier, L.

AU - Le Milbeau, C.

AU - Monnin, L.

AU - Guegan, Regis

PY - 2016/1/1

Y1 - 2016/1/1

N2 - The removal of a Pharmaceutically Active Compound (PhAC) pool using a well referenced clay mineral from Wyoming (SWy-2) as a geosorbent was studied for a better understanding of the environmental fate. As expected, the selected material shows its particular adsorption properties to PhAC under different experimental conditions with two main features depending on the chemical nature of the emerging micro-pollutants. Cationic PhACs, for which the driving force for their adsorption results from electrostatic interaction via the exchange with the inorganic cations of the clay mineral, are almost completely removed for all studied experimental conditions where it appears that the S/L ratio plays a minor role and the only one limitation for their removal is the cation exchange capacity of the adsorbent. In contrast, anionic and neutral PhACs are adsorbed to the clay mineral surface (silanol groups on the sheet edges, inorganic cations...) through other interactional mechanisms involving ion-dipole, van der Waals interaction, leading to a competition of all organic molecules where their chemical nature (electric charge, hydrophobicity) may also play a role in their adsorption. While the adsorption of ketoprofen, naproxen, diclofenac and salicylic acid anionic PhACs slightly increases with the increase of the S/L ratio, the removal of the neutral and the other anionic PhACs (gemfibrozil and ibuprofen) seems to be independent of that ratio and is particularly enhanced. The efficiency of the removal for a global pool of PhACs even in low S/L ratio stresses the control of the selected natural minerals on the dynamics of PhACs in the environment.

AB - The removal of a Pharmaceutically Active Compound (PhAC) pool using a well referenced clay mineral from Wyoming (SWy-2) as a geosorbent was studied for a better understanding of the environmental fate. As expected, the selected material shows its particular adsorption properties to PhAC under different experimental conditions with two main features depending on the chemical nature of the emerging micro-pollutants. Cationic PhACs, for which the driving force for their adsorption results from electrostatic interaction via the exchange with the inorganic cations of the clay mineral, are almost completely removed for all studied experimental conditions where it appears that the S/L ratio plays a minor role and the only one limitation for their removal is the cation exchange capacity of the adsorbent. In contrast, anionic and neutral PhACs are adsorbed to the clay mineral surface (silanol groups on the sheet edges, inorganic cations...) through other interactional mechanisms involving ion-dipole, van der Waals interaction, leading to a competition of all organic molecules where their chemical nature (electric charge, hydrophobicity) may also play a role in their adsorption. While the adsorption of ketoprofen, naproxen, diclofenac and salicylic acid anionic PhACs slightly increases with the increase of the S/L ratio, the removal of the neutral and the other anionic PhACs (gemfibrozil and ibuprofen) seems to be independent of that ratio and is particularly enhanced. The efficiency of the removal for a global pool of PhACs even in low S/L ratio stresses the control of the selected natural minerals on the dynamics of PhACs in the environment.

UR - http://www.scopus.com/inward/record.url?scp=84978374491&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84978374491&partnerID=8YFLogxK

U2 - 10.1039/c6ra10655b

DO - 10.1039/c6ra10655b

M3 - Article

VL - 6

SP - 65257

EP - 65265

JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 69

ER -