Cone visual pigments are present in gecko rod cells

Daisuke Kojima, Toshiyuki Okano, Yoshitaka Fukada, Yoshinori Shichida, Tôru Yoshizawa, Thomas G. Ebrey

Research output: Contribution to journalArticle

98 Citations (Scopus)

Abstract

The Tokay gecko (Gekko gekko), a nocturnal lizard, has two kinds of visual pigments, P467 and P521. In spite of the pure-rod morphology of the photoreceptor cells, the biochemical properties of P521 and P467 resemble those of iodopsin (the chicken red-sensitive cone visual pigment) and rhodopsin, respectively. We have found that the amino acid sequence of P521 deduced from the cDNA was very similar to that of iodopsin. In addition, P467 has the highest homology with the chicken green-sensitive cone visual pigment, although it also has a relatively high homology with rhodopsins. These results give additional strength to the transmutation theory of Walls [Walls, G. L. (1934) Am. J. Ophthalmol. 17, 892-915], who proposed that the rod-shaped photoreceptor cells of lizards have been derived from ancestral cone-like photoreceptors. Apparently amino acid sequences of visual pigments are less changeable than the morphology of the photoreceptor cells in the course of evolution.

Original languageEnglish
Pages (from-to)6841-6845
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume89
Issue number15
Publication statusPublished - 1992
Externally publishedYes

Fingerprint

Retinal Pigments
Lizards
Retinal Rod Photoreceptor Cells
Rhodopsin
Amino Acid Sequence
Retinal Cone Photoreceptor Cells
Photoreceptor Cells
Chickens
Complementary DNA
iodopsin

Keywords

  • cDNA cloning
  • Rod and cone
  • Transmutation theory

ASJC Scopus subject areas

  • Genetics
  • General

Cite this

Kojima, D., Okano, T., Fukada, Y., Shichida, Y., Yoshizawa, T., & Ebrey, T. G. (1992). Cone visual pigments are present in gecko rod cells. Proceedings of the National Academy of Sciences of the United States of America, 89(15), 6841-6845.

Cone visual pigments are present in gecko rod cells. / Kojima, Daisuke; Okano, Toshiyuki; Fukada, Yoshitaka; Shichida, Yoshinori; Yoshizawa, Tôru; Ebrey, Thomas G.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, No. 15, 1992, p. 6841-6845.

Research output: Contribution to journalArticle

Kojima, D, Okano, T, Fukada, Y, Shichida, Y, Yoshizawa, T & Ebrey, TG 1992, 'Cone visual pigments are present in gecko rod cells', Proceedings of the National Academy of Sciences of the United States of America, vol. 89, no. 15, pp. 6841-6845.
Kojima, Daisuke ; Okano, Toshiyuki ; Fukada, Yoshitaka ; Shichida, Yoshinori ; Yoshizawa, Tôru ; Ebrey, Thomas G. / Cone visual pigments are present in gecko rod cells. In: Proceedings of the National Academy of Sciences of the United States of America. 1992 ; Vol. 89, No. 15. pp. 6841-6845.
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