Construction of protein-crosslinked nanogels with vitamin B6 bearing polysaccharide

Yoshihiro Sasaki, Yuji Tsuchido, Shin Ichi Sawada, Kazunari Akiyoshi

Research output: Contribution to journalArticle

24 Citations (Scopus)


Protein-crosslinked nanogels were prepared by introducing vitamin B 6 (pyridoxal) to hydrophilic polysaccharide. The pH dependence of Schiff base formation was utilized to generate a pH-sensitive nanogel system. This approach represents a new method to prepare hybrid nanogels crosslinked with biomolecules.

Original languageEnglish
Pages (from-to)1267-1270
Number of pages4
JournalPolymer Chemistry
Issue number6
Publication statusPublished - 2011 Jun 1
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Polymers and Plastics
  • Organic Chemistry

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