Abstract
We describe a novel method for generation of femtolitre-order monodisperse droplets using a multistage dividing microfluidic channel. A droplet is uniformly divided into 16 parts in a four-stage microfluidic channel without the need for external equipment. The droplets become smaller as the cross-junction part becomes narrower (range from 87.8 to 9.05 pL). Central micropillar structures at each bifurcation reduce the difference in the channel resistance throughout the microchannel between two side-channel that is divided by micropillar structures, which enables the equivalent division of femtolitre-order-volume droplets. After the fourth bifurcation, the minimum radius of a daughter droplet is 5 μm (ca. 524 fL) and the coefficient variation is 0.51%. The generation rate is 3800 droplets/s in a single-droplet generation line.
Original language | English |
---|---|
Pages (from-to) | S33-S37 |
Journal | Current Applied Physics |
Volume | 12 |
Issue number | SUPPL.3 |
DOIs | |
Publication status | Published - 2012 Dec |
Keywords
- Droplet
- Femtolitre droplet
- Microfluidics
- Multistage division
ASJC Scopus subject areas
- Materials Science(all)
- Physics and Astronomy(all)