Continuously maintaining positive flow avoids endocardial suction of a rotary blood pump with left ventricular bypass

Takehide Akimoto, Kenji Yamazaki, Philip Litwak, Kenneth N. Litwak, Osamu Tagusari, Toshio Mori, James F. Antaki, Marina V. Kameneva, Mary J. Watach, Mitsuo Umezu, Jun Tomioka, Robert L. Kormos, Hitoshi Koyanagi, Bartley P. Griffith

    Research output: Contribution to journalArticle

    10 Citations (Scopus)

    Abstract

    This study showed the usefulness of maintaining positive pump flow to avoid endocardial suction and as an assist bypass. Three calves were implanted with centrifugal pumps. Hemodynamics and pump parameters were measured at varying pump speeds (from 1,100 to 2,300 rpm). In each test pump, speed was adjusted to create 3 hemodynamic states: Both positive and negative flow (PNF), positive and zero flow (PZF), and continuously positive flow (CPF). The pump flow volume was determined during systole (Vs) and diastole (Vd). Vs in PNF was 29.6 ml and was not significantly different from Vs in PZF (p > 0.15). Vd in PNF was significantly different from Vd in PZF (p < 0.05). All bypass rates of PNF were over 30% of pulmonary flow. All PZF bypass rates were between the PNF rate and the CPF rate. These data showed that PZF satisfied the minimum requirement of assist flow and was under 100% bypass. Thus, PZF may avoid endocardial suction.

    Original languageEnglish
    Pages (from-to)606-610
    Number of pages5
    JournalArtificial Organs
    Volume24
    Issue number8
    DOIs
    Publication statusPublished - 2000

    Fingerprint

    Diastole
    Suction
    Blood
    Pumps
    Hemodynamics
    Systole
    Flow rate
    Centrifugal pumps
    Lung

    Keywords

    • Centrifugal blood pump
    • Endocardial suction-pump flow volume
    • Hemodynamics
    • Left ventricular assist device
    • Regurgitate flow

    ASJC Scopus subject areas

    • Biophysics

    Cite this

    Akimoto, T., Yamazaki, K., Litwak, P., Litwak, K. N., Tagusari, O., Mori, T., ... Griffith, B. P. (2000). Continuously maintaining positive flow avoids endocardial suction of a rotary blood pump with left ventricular bypass. Artificial Organs, 24(8), 606-610. https://doi.org/10.1046/j.1525-1594.2000.06581.x

    Continuously maintaining positive flow avoids endocardial suction of a rotary blood pump with left ventricular bypass. / Akimoto, Takehide; Yamazaki, Kenji; Litwak, Philip; Litwak, Kenneth N.; Tagusari, Osamu; Mori, Toshio; Antaki, James F.; Kameneva, Marina V.; Watach, Mary J.; Umezu, Mitsuo; Tomioka, Jun; Kormos, Robert L.; Koyanagi, Hitoshi; Griffith, Bartley P.

    In: Artificial Organs, Vol. 24, No. 8, 2000, p. 606-610.

    Research output: Contribution to journalArticle

    Akimoto, T, Yamazaki, K, Litwak, P, Litwak, KN, Tagusari, O, Mori, T, Antaki, JF, Kameneva, MV, Watach, MJ, Umezu, M, Tomioka, J, Kormos, RL, Koyanagi, H & Griffith, BP 2000, 'Continuously maintaining positive flow avoids endocardial suction of a rotary blood pump with left ventricular bypass', Artificial Organs, vol. 24, no. 8, pp. 606-610. https://doi.org/10.1046/j.1525-1594.2000.06581.x
    Akimoto, Takehide ; Yamazaki, Kenji ; Litwak, Philip ; Litwak, Kenneth N. ; Tagusari, Osamu ; Mori, Toshio ; Antaki, James F. ; Kameneva, Marina V. ; Watach, Mary J. ; Umezu, Mitsuo ; Tomioka, Jun ; Kormos, Robert L. ; Koyanagi, Hitoshi ; Griffith, Bartley P. / Continuously maintaining positive flow avoids endocardial suction of a rotary blood pump with left ventricular bypass. In: Artificial Organs. 2000 ; Vol. 24, No. 8. pp. 606-610.
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