Abstract
Reaction of phenols in dimethyl carbonate in the presence of cesium carbonate at 120-160° C gave aryl methyl ethers in good yields, whereas the reaction of aliphatic alcohols gave the corresponding alkyl carbonates. This method provides a useful synthetic method for preparation of various aryl methyl ethers without using toxic methyl iodide or dimethyl sulfate. O-Methylation of the aromatic hydroxy group of estradiol was carried out in 2 steps without protection of the alcoholic hydroxy group in the same molecule.
| Original language | English |
|---|---|
| Pages (from-to) | 1063-1064 |
| Number of pages | 2 |
| Journal | Synlett |
| Issue number | 10 |
| Publication status | Published - 1998 Oct |
ASJC Scopus subject areas
- Organic Chemistry