Coordination property of poly(1-vinyl-2-methylimidazole)-heme complexes

Eishun Tsuchida, Hiroyuki Nishide, Hirokazu Ohno

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Poly(1-vinyl-2-methylimidazole) and poly(1-vinyl-2-methylimidazole-co-1-vinylpyrrolidone) predominantly form five-coordinate heme complexes in aqueous solution. The apparent formation constants (K) of the heme complexes were estimated spectroscopically. The K values of the polymer-heme complexes were about 102 to 103 times those of the corresponding monomeric ones. These large K values were canceled by adding poly(1-vinylpyrrolidone), alcohol, or dimethylformamide. The viscometric measurement of the polymer-heme solution showed that the polymer complex took a compact shape. These results indicate a hydrophobic interaction of heme with the polymer-ligand. Poly(1-vinyl-2-methylimidazole) could form the five-coordinate heme complex, even in the presence of a large amount of imidazole.

Original languageEnglish
Pages (from-to)283-291
Number of pages9
JournalJournal of Inorganic Biochemistry
Volume17
Issue number4
DOIs
Publication statusPublished - 1982

Fingerprint

Heme
Polymers
Dimethylformamide
Hydrophobic and Hydrophilic Interactions
2-methylimidazole
Alcohols
Ligands

ASJC Scopus subject areas

  • Biochemistry
  • Inorganic Chemistry

Cite this

Coordination property of poly(1-vinyl-2-methylimidazole)-heme complexes. / Tsuchida, Eishun; Nishide, Hiroyuki; Ohno, Hirokazu.

In: Journal of Inorganic Biochemistry, Vol. 17, No. 4, 1982, p. 283-291.

Research output: Contribution to journalArticle

@article{47f0737b4f0b44d4b3aa36f1a52410b8,
title = "Coordination property of poly(1-vinyl-2-methylimidazole)-heme complexes",
abstract = "Poly(1-vinyl-2-methylimidazole) and poly(1-vinyl-2-methylimidazole-co-1-vinylpyrrolidone) predominantly form five-coordinate heme complexes in aqueous solution. The apparent formation constants (K) of the heme complexes were estimated spectroscopically. The K values of the polymer-heme complexes were about 102 to 103 times those of the corresponding monomeric ones. These large K values were canceled by adding poly(1-vinylpyrrolidone), alcohol, or dimethylformamide. The viscometric measurement of the polymer-heme solution showed that the polymer complex took a compact shape. These results indicate a hydrophobic interaction of heme with the polymer-ligand. Poly(1-vinyl-2-methylimidazole) could form the five-coordinate heme complex, even in the presence of a large amount of imidazole.",
author = "Eishun Tsuchida and Hiroyuki Nishide and Hirokazu Ohno",
year = "1982",
doi = "10.1016/S0162-0134(00)80089-6",
language = "English",
volume = "17",
pages = "283--291",
journal = "Journal of Inorganic Biochemistry",
issn = "0162-0134",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Coordination property of poly(1-vinyl-2-methylimidazole)-heme complexes

AU - Tsuchida, Eishun

AU - Nishide, Hiroyuki

AU - Ohno, Hirokazu

PY - 1982

Y1 - 1982

N2 - Poly(1-vinyl-2-methylimidazole) and poly(1-vinyl-2-methylimidazole-co-1-vinylpyrrolidone) predominantly form five-coordinate heme complexes in aqueous solution. The apparent formation constants (K) of the heme complexes were estimated spectroscopically. The K values of the polymer-heme complexes were about 102 to 103 times those of the corresponding monomeric ones. These large K values were canceled by adding poly(1-vinylpyrrolidone), alcohol, or dimethylformamide. The viscometric measurement of the polymer-heme solution showed that the polymer complex took a compact shape. These results indicate a hydrophobic interaction of heme with the polymer-ligand. Poly(1-vinyl-2-methylimidazole) could form the five-coordinate heme complex, even in the presence of a large amount of imidazole.

AB - Poly(1-vinyl-2-methylimidazole) and poly(1-vinyl-2-methylimidazole-co-1-vinylpyrrolidone) predominantly form five-coordinate heme complexes in aqueous solution. The apparent formation constants (K) of the heme complexes were estimated spectroscopically. The K values of the polymer-heme complexes were about 102 to 103 times those of the corresponding monomeric ones. These large K values were canceled by adding poly(1-vinylpyrrolidone), alcohol, or dimethylformamide. The viscometric measurement of the polymer-heme solution showed that the polymer complex took a compact shape. These results indicate a hydrophobic interaction of heme with the polymer-ligand. Poly(1-vinyl-2-methylimidazole) could form the five-coordinate heme complex, even in the presence of a large amount of imidazole.

UR - http://www.scopus.com/inward/record.url?scp=49049134105&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49049134105&partnerID=8YFLogxK

U2 - 10.1016/S0162-0134(00)80089-6

DO - 10.1016/S0162-0134(00)80089-6

M3 - Article

VL - 17

SP - 283

EP - 291

JO - Journal of Inorganic Biochemistry

JF - Journal of Inorganic Biochemistry

SN - 0162-0134

IS - 4

ER -