Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimates

Kenji Takizawa, Ryo Torii, Hirokazu Takagi, Tayfun E. Tezduyar, Xiao Y. Xu

    Research output: Contribution to journalArticle

    22 Citations (Scopus)

    Abstract

    We propose a method for coronary arterial dynamics computation with medical-image-based time-dependent anatomical models. The objective is to improve the computational analysis of coronary arteries for better understanding of the links between the atherosclerosis development and mechanical stimuli such as endothelial wall shear stress and structural stress in the arterial wall. The method has two components. The first one is element-based zero-stress (ZS) state estimation, which is an alternative to prestress calculation. The second one is a “mixed ZS state” approach, where the ZS states for different elements in the structural mechanics mesh are estimated with reference configurations based on medical images coming from different instants within the cardiac cycle. We demonstrate the robustness of the method in a patient-specific coronary arterial dynamics computation where the motion of a thin strip along the arterial surface and two cut surfaces at the arterial ends is specified to match the motion extracted from the medical images.

    Original languageEnglish
    Pages (from-to)1047-1053
    Number of pages7
    JournalComputational Mechanics
    Volume54
    Issue number4
    DOIs
    Publication statusPublished - 2014 Oct 1

    Fingerprint

    Medical Image
    Zero
    Estimate
    Atherosclerosis
    Prestress
    Structural Mechanics
    Wall Shear Stress
    Motion
    Coronary Artery
    Computational Analysis
    State Estimation
    State estimation
    Instant
    Model
    Cardiac
    Strip
    Shear stress
    Mechanics
    Mesh
    Robustness

    Keywords

    • Coronary arterial dynamics
    • Coronary atherosclerosis
    • Element-based zero-stress state estimate
    • Medical-image-based data
    • Mixed zero-stress state
    • Time-dependent anatomical model

    ASJC Scopus subject areas

    • Computational Theory and Mathematics
    • Mechanical Engineering
    • Ocean Engineering
    • Applied Mathematics
    • Computational Mathematics

    Cite this

    Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimates. / Takizawa, Kenji; Torii, Ryo; Takagi, Hirokazu; Tezduyar, Tayfun E.; Xu, Xiao Y.

    In: Computational Mechanics, Vol. 54, No. 4, 01.10.2014, p. 1047-1053.

    Research output: Contribution to journalArticle

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    AU - Xu, Xiao Y.

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