Abstract
We propose a method for coronary arterial dynamics computation with medical-image-based time-dependent anatomical models. The objective is to improve the computational analysis of coronary arteries for better understanding of the links between the atherosclerosis development and mechanical stimuli such as endothelial wall shear stress and structural stress in the arterial wall. The method has two components. The first one is element-based zero-stress (ZS) state estimation, which is an alternative to prestress calculation. The second one is a “mixed ZS state” approach, where the ZS states for different elements in the structural mechanics mesh are estimated with reference configurations based on medical images coming from different instants within the cardiac cycle. We demonstrate the robustness of the method in a patient-specific coronary arterial dynamics computation where the motion of a thin strip along the arterial surface and two cut surfaces at the arterial ends is specified to match the motion extracted from the medical images.
| Original language | English |
|---|---|
| Pages (from-to) | 1047-1053 |
| Number of pages | 7 |
| Journal | Computational Mechanics |
| Volume | 54 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2014 Oct 1 |
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Keywords
- Coronary arterial dynamics
- Coronary atherosclerosis
- Element-based zero-stress state estimate
- Medical-image-based data
- Mixed zero-stress state
- Time-dependent anatomical model
ASJC Scopus subject areas
- Computational Theory and Mathematics
- Mechanical Engineering
- Ocean Engineering
- Applied Mathematics
- Computational Mathematics
Cite this
Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimates. / Takizawa, Kenji; Torii, Ryo; Takagi, Hirokazu; Tezduyar, Tayfun E.; Xu, Xiao Y.
In: Computational Mechanics, Vol. 54, No. 4, 01.10.2014, p. 1047-1053.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Coronary arterial dynamics computation with medical-image-based time-dependent anatomical models and element-based zero-stress state estimates
AU - Takizawa, Kenji
AU - Torii, Ryo
AU - Takagi, Hirokazu
AU - Tezduyar, Tayfun E.
AU - Xu, Xiao Y.
PY - 2014/10/1
Y1 - 2014/10/1
N2 - We propose a method for coronary arterial dynamics computation with medical-image-based time-dependent anatomical models. The objective is to improve the computational analysis of coronary arteries for better understanding of the links between the atherosclerosis development and mechanical stimuli such as endothelial wall shear stress and structural stress in the arterial wall. The method has two components. The first one is element-based zero-stress (ZS) state estimation, which is an alternative to prestress calculation. The second one is a “mixed ZS state” approach, where the ZS states for different elements in the structural mechanics mesh are estimated with reference configurations based on medical images coming from different instants within the cardiac cycle. We demonstrate the robustness of the method in a patient-specific coronary arterial dynamics computation where the motion of a thin strip along the arterial surface and two cut surfaces at the arterial ends is specified to match the motion extracted from the medical images.
AB - We propose a method for coronary arterial dynamics computation with medical-image-based time-dependent anatomical models. The objective is to improve the computational analysis of coronary arteries for better understanding of the links between the atherosclerosis development and mechanical stimuli such as endothelial wall shear stress and structural stress in the arterial wall. The method has two components. The first one is element-based zero-stress (ZS) state estimation, which is an alternative to prestress calculation. The second one is a “mixed ZS state” approach, where the ZS states for different elements in the structural mechanics mesh are estimated with reference configurations based on medical images coming from different instants within the cardiac cycle. We demonstrate the robustness of the method in a patient-specific coronary arterial dynamics computation where the motion of a thin strip along the arterial surface and two cut surfaces at the arterial ends is specified to match the motion extracted from the medical images.
KW - Coronary arterial dynamics
KW - Coronary atherosclerosis
KW - Element-based zero-stress state estimate
KW - Medical-image-based data
KW - Mixed zero-stress state
KW - Time-dependent anatomical model
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U2 - 10.1007/s00466-014-1049-6
DO - 10.1007/s00466-014-1049-6
M3 - Article
VL - 54
SP - 1047
EP - 1053
JO - Computational Mechanics
JF - Computational Mechanics
SN - 0178-7675
IS - 4
ER -