Correlation between electroencephalography and heart rate variability during sleep

Mina Ako, Tokuhiro Kawara, Sunao Uchida, Shinichi Miyazaki, Kyoko Nishihara, Junko Mukai, Kenzo Hirao, Junya Ako, Yoshiro Okubo

Research output: Contribution to journalArticle

85 Citations (Scopus)

Abstract

It is known that autonomic nervous activities change in correspondence with sleep stages. However, the characteristics of continuous fluctuations in nocturnal autonomic nerve tone have not been clarified in detail. The study aimed to determine the possible correlation between the electroencephalogram (EEG) and autonomic nervous activities, and to clarify in detail the nocturnal fluctuations in autonomic nerve activities. Overnight EEGs and electrocardiograms of seven healthy males were obtained. These EEGs were analyzed by fast Fourier transformation algorithm to extract delta, sigma and beta power. Heart rate and heart rate variability (HRV) were calculated in consecutive 5-min epochs. The HRV indices of low frequency (LF), high frequency (HF) and LF/HF ratio were calculated from the spectral analysis of R-R intervals. The sleep stages were manually scored according to Rechtschaffen and Kales' criteria. Low frequency and LF/HF were significantly lower during non-rapid eye movement (NREM) than REM, and were lower in stages 3 and 4 than in stages 1 and 2. Furthermore, delta EEG showed inverse correlations with LF (r=-0.44, P<0.001) and LF/HF (r=-0.41, P<0.001). In contrast, HF differed neither between REM and NREM nor among NREM sleep stages. Detailed analysis revealed that correlation was evident from the first to third NREM, but not in the fourth and fifth NREM. Delta EEG power showed negative correlations with LF and LF/HF, suggesting that sympathetic nervous activities continuously fluctuate in accordance with sleep deepening and lightening.

Original languageEnglish
Pages (from-to)59-65
Number of pages7
JournalPsychiatry and Clinical Neurosciences
Volume57
Issue number1
DOIs
Publication statusPublished - 2003 Feb
Externally publishedYes

Fingerprint

Eye Movements
Electroencephalography
Sleep
Heart Rate
Sleep Stages
Autonomic Pathways
Brassica
Electrocardiography
Power (Psychology)

Keywords

  • Delta wave
  • Heart rate variability
  • Sleep electroencephalogram
  • Spectral analysis

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychiatry and Mental health
  • Neuroscience(all)

Cite this

Ako, M., Kawara, T., Uchida, S., Miyazaki, S., Nishihara, K., Mukai, J., ... Okubo, Y. (2003). Correlation between electroencephalography and heart rate variability during sleep. Psychiatry and Clinical Neurosciences, 57(1), 59-65. https://doi.org/10.1046/j.1440-1819.2003.01080.x

Correlation between electroencephalography and heart rate variability during sleep. / Ako, Mina; Kawara, Tokuhiro; Uchida, Sunao; Miyazaki, Shinichi; Nishihara, Kyoko; Mukai, Junko; Hirao, Kenzo; Ako, Junya; Okubo, Yoshiro.

In: Psychiatry and Clinical Neurosciences, Vol. 57, No. 1, 02.2003, p. 59-65.

Research output: Contribution to journalArticle

Ako, M, Kawara, T, Uchida, S, Miyazaki, S, Nishihara, K, Mukai, J, Hirao, K, Ako, J & Okubo, Y 2003, 'Correlation between electroencephalography and heart rate variability during sleep', Psychiatry and Clinical Neurosciences, vol. 57, no. 1, pp. 59-65. https://doi.org/10.1046/j.1440-1819.2003.01080.x
Ako, Mina ; Kawara, Tokuhiro ; Uchida, Sunao ; Miyazaki, Shinichi ; Nishihara, Kyoko ; Mukai, Junko ; Hirao, Kenzo ; Ako, Junya ; Okubo, Yoshiro. / Correlation between electroencephalography and heart rate variability during sleep. In: Psychiatry and Clinical Neurosciences. 2003 ; Vol. 57, No. 1. pp. 59-65.
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