Cortical Correlates of Locomotor Muscle Synergy Activation in Humans: An Electroencephalographic Decoding Study

Hikaru Yokoyama, Naotsugu Kaneko, Tetsuya Ogawa, Noritaka Kawashima, Katsumi Watanabe, Kimitaka Nakazawa

Research output: Contribution to journalArticle

Abstract

Muscular control during walking is believed to be simplified by the coactivation of muscles called muscle synergies. Although significant corticomuscular connectivity during walking has been reported, the level at which the cortical activity is involved in muscle activity (muscle synergy or individual muscle level)remains unclear. Here we examined cortical correlates of muscle activation during walking by brain decoding of activation of muscle synergies and individual muscles from electroencephalographic signals. We demonstrated that the activation of locomotor muscle synergies was decoded from slow cortical waves. In addition, the decoding accuracy for muscle synergies was greater than that for individual muscles and the decoding of individual muscle activation was based on muscle-synergy-related cortical information. These results indicate the cortical correlates of locomotor muscle synergy activation. These findings expand our understanding of the relationships between brain and locomotor muscle synergies and could accelerate the development of effective brain-machine interfaces for walking rehabilitation.

Original languageEnglish
Pages (from-to)623-639
Number of pages17
JournaliScience
Volume15
DOIs
Publication statusPublished - 2019 May 31

Fingerprint

Muscles
Walking
Brain-Computer Interfaces
Brain
Rehabilitation

Keywords

  • Biomechanics
  • Human Physiology
  • Neuroscience

ASJC Scopus subject areas

  • General

Cite this

Cortical Correlates of Locomotor Muscle Synergy Activation in Humans : An Electroencephalographic Decoding Study. / Yokoyama, Hikaru; Kaneko, Naotsugu; Ogawa, Tetsuya; Kawashima, Noritaka; Watanabe, Katsumi; Nakazawa, Kimitaka.

In: iScience, Vol. 15, 31.05.2019, p. 623-639.

Research output: Contribution to journalArticle

Yokoyama, Hikaru ; Kaneko, Naotsugu ; Ogawa, Tetsuya ; Kawashima, Noritaka ; Watanabe, Katsumi ; Nakazawa, Kimitaka. / Cortical Correlates of Locomotor Muscle Synergy Activation in Humans : An Electroencephalographic Decoding Study. In: iScience. 2019 ; Vol. 15. pp. 623-639.
@article{945c5f5b503645fbb9f30a20bb31354d,
title = "Cortical Correlates of Locomotor Muscle Synergy Activation in Humans: An Electroencephalographic Decoding Study",
abstract = "Muscular control during walking is believed to be simplified by the coactivation of muscles called muscle synergies. Although significant corticomuscular connectivity during walking has been reported, the level at which the cortical activity is involved in muscle activity (muscle synergy or individual muscle level)remains unclear. Here we examined cortical correlates of muscle activation during walking by brain decoding of activation of muscle synergies and individual muscles from electroencephalographic signals. We demonstrated that the activation of locomotor muscle synergies was decoded from slow cortical waves. In addition, the decoding accuracy for muscle synergies was greater than that for individual muscles and the decoding of individual muscle activation was based on muscle-synergy-related cortical information. These results indicate the cortical correlates of locomotor muscle synergy activation. These findings expand our understanding of the relationships between brain and locomotor muscle synergies and could accelerate the development of effective brain-machine interfaces for walking rehabilitation.",
keywords = "Biomechanics, Human Physiology, Neuroscience",
author = "Hikaru Yokoyama and Naotsugu Kaneko and Tetsuya Ogawa and Noritaka Kawashima and Katsumi Watanabe and Kimitaka Nakazawa",
year = "2019",
month = "5",
day = "31",
doi = "10.1016/j.isci.2019.04.008",
language = "English",
volume = "15",
pages = "623--639",
journal = "iScience",
issn = "2589-0042",
publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - Cortical Correlates of Locomotor Muscle Synergy Activation in Humans

T2 - An Electroencephalographic Decoding Study

AU - Yokoyama, Hikaru

AU - Kaneko, Naotsugu

AU - Ogawa, Tetsuya

AU - Kawashima, Noritaka

AU - Watanabe, Katsumi

AU - Nakazawa, Kimitaka

PY - 2019/5/31

Y1 - 2019/5/31

N2 - Muscular control during walking is believed to be simplified by the coactivation of muscles called muscle synergies. Although significant corticomuscular connectivity during walking has been reported, the level at which the cortical activity is involved in muscle activity (muscle synergy or individual muscle level)remains unclear. Here we examined cortical correlates of muscle activation during walking by brain decoding of activation of muscle synergies and individual muscles from electroencephalographic signals. We demonstrated that the activation of locomotor muscle synergies was decoded from slow cortical waves. In addition, the decoding accuracy for muscle synergies was greater than that for individual muscles and the decoding of individual muscle activation was based on muscle-synergy-related cortical information. These results indicate the cortical correlates of locomotor muscle synergy activation. These findings expand our understanding of the relationships between brain and locomotor muscle synergies and could accelerate the development of effective brain-machine interfaces for walking rehabilitation.

AB - Muscular control during walking is believed to be simplified by the coactivation of muscles called muscle synergies. Although significant corticomuscular connectivity during walking has been reported, the level at which the cortical activity is involved in muscle activity (muscle synergy or individual muscle level)remains unclear. Here we examined cortical correlates of muscle activation during walking by brain decoding of activation of muscle synergies and individual muscles from electroencephalographic signals. We demonstrated that the activation of locomotor muscle synergies was decoded from slow cortical waves. In addition, the decoding accuracy for muscle synergies was greater than that for individual muscles and the decoding of individual muscle activation was based on muscle-synergy-related cortical information. These results indicate the cortical correlates of locomotor muscle synergy activation. These findings expand our understanding of the relationships between brain and locomotor muscle synergies and could accelerate the development of effective brain-machine interfaces for walking rehabilitation.

KW - Biomechanics

KW - Human Physiology

KW - Neuroscience

UR - http://www.scopus.com/inward/record.url?scp=85066290345&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85066290345&partnerID=8YFLogxK

U2 - 10.1016/j.isci.2019.04.008

DO - 10.1016/j.isci.2019.04.008

M3 - Article

AN - SCOPUS:85066290345

VL - 15

SP - 623

EP - 639

JO - iScience

JF - iScience

SN - 2589-0042

ER -