Cross coupling between sp 3-carbon and sp 3-carbon using a diborylmethane derivative at room temperature

Kohei Endo, Takahiro Ohkubo, Takafumi Ishioka, Takanori Shibata

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    65 Citations (Scopus)

    Abstract

    A novel example of the Suzuki-Miyaura cross-coupling reaction between sp 3-carbon and sp 3-carbon is described. The reaction of a diborylmethane derivative with allyl halides or benzyl halides proceeded efficiently in the presence of appropriate Pd-catalysts at room temperature. The present approaches provide functionalized homoallylboronates and alkylboronates with excellent regio- and chemoselectivities.

    Original languageEnglish
    Pages (from-to)4826-4831
    Number of pages6
    JournalJournal of Organic Chemistry
    Volume77
    Issue number10
    DOIs
    Publication statusPublished - 2012 May 18

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    ASJC Scopus subject areas

    • Organic Chemistry

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