Cross coupling between sp 3-carbon and sp 3-carbon using a diborylmethane derivative at room temperature

Kohei Endo, Takahiro Ohkubo, Takafumi Ishioka, Takanori Shibata

    Research output: Contribution to journalArticle

    65 Citations (Scopus)


    A novel example of the Suzuki-Miyaura cross-coupling reaction between sp 3-carbon and sp 3-carbon is described. The reaction of a diborylmethane derivative with allyl halides or benzyl halides proceeded efficiently in the presence of appropriate Pd-catalysts at room temperature. The present approaches provide functionalized homoallylboronates and alkylboronates with excellent regio- and chemoselectivities.

    Original languageEnglish
    Pages (from-to)4826-4831
    Number of pages6
    JournalJournal of Organic Chemistry
    Issue number10
    Publication statusPublished - 2012 May 18


    ASJC Scopus subject areas

    • Organic Chemistry

    Cite this