Cross coupling between sp 3-carbon and sp 3-carbon using a diborylmethane derivative at room temperature

Kohei Endo, Takahiro Ohkubo, Takafumi Ishioka, Takanori Shibata

    Research output: Contribution to journalArticle

    63 Citations (Scopus)

    Abstract

    A novel example of the Suzuki-Miyaura cross-coupling reaction between sp 3-carbon and sp 3-carbon is described. The reaction of a diborylmethane derivative with allyl halides or benzyl halides proceeded efficiently in the presence of appropriate Pd-catalysts at room temperature. The present approaches provide functionalized homoallylboronates and alkylboronates with excellent regio- and chemoselectivities.

    Original languageEnglish
    Pages (from-to)4826-4831
    Number of pages6
    JournalJournal of Organic Chemistry
    Volume77
    Issue number10
    DOIs
    Publication statusPublished - 2012 May 18

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    Carbon
    Derivatives
    Regioselectivity
    Temperature
    Catalysts

    ASJC Scopus subject areas

    • Organic Chemistry

    Cite this

    Cross coupling between sp 3-carbon and sp 3-carbon using a diborylmethane derivative at room temperature. / Endo, Kohei; Ohkubo, Takahiro; Ishioka, Takafumi; Shibata, Takanori.

    In: Journal of Organic Chemistry, Vol. 77, No. 10, 18.05.2012, p. 4826-4831.

    Research output: Contribution to journalArticle

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    AU - Shibata, Takanori

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