CT-guided stereotactic brachytherapy in deep-seated malignant gliomas--interstitial irradiation by double-catheter after-loading method

M. Notani, K. Amano, H. Kawamura, T. Tanikawa, H. Kawabatake, H. Iseki, T. Shiwaku, T. Nagao, Y. Iwata, T. Taira

    Research output: Contribution to journalArticle

    Abstract

    CT-guided stereotactic brachytherapy has been performed for the deep-seated malignant gliomas using the double-catheter after-loading method. The catheter system consists of two coaxial polyethylene tubes with closed tips. The outer catheter is 3.0 mm in outer diameter and 2.4 mm in inner diameter. The inner catheter is 2.0 mm in outside diameter and 1.4 mm in inside diameter, and contains the radioactive sources. Localization of the target volume is determined by the preoperative findings of computed tomography (CT), magnetic resonance imaging (MRI), and cerebral angiography. Dosimetry and dose planning are so finalized for the target volume as to be irradiated interstitially more than tumoricidal dose. After stereotactic biopsy of the deep-seated brain tumors, stereotactic implantation of the outer catheters is performed using Iseki Stereotactic System in the CT room. Burr holes had been previously opened in the operating room. The inner catheters containing nonradioactive sources (dummy sources) are inserted, and skull X-p is taken to confirm the position of the dummy sources, and to calculate the dosimetry by computer. The inner catheters are replaced with catheters containing radioactive sources (226Ra) in the irradiation room. 226Ra sources deliver at least 500 rads/day (approximately 20 rads/hr) to the target volume as interstitial irradiation. Two patients of malignant gliomas treated with this procedure were shown as representative cases. These patients underwent CT-guided stereotactic brachytherapy as "boost" combined with conventional external irradiation.(ABSTRACT TRUNCATED AT 250 WORDS)

    Original languageEnglish
    Pages (from-to)251-258
    Number of pages8
    JournalNeurological Surgery
    Volume15
    Issue number3
    Publication statusPublished - 1987 Mar 1

    ASJC Scopus subject areas

    • Surgery
    • Clinical Neurology

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  • Cite this

    Notani, M., Amano, K., Kawamura, H., Tanikawa, T., Kawabatake, H., Iseki, H., Shiwaku, T., Nagao, T., Iwata, Y., & Taira, T. (1987). CT-guided stereotactic brachytherapy in deep-seated malignant gliomas--interstitial irradiation by double-catheter after-loading method. Neurological Surgery, 15(3), 251-258.