Current rectification with poly-L-lysine-coated quartz nanopipettes

Senkei Umehara, Nader Pourmand, Chris D. Webb, Ronald W. Davis, Kenji Yasuda, Miloslav Karhanek

Research output: Contribution to journalArticle

145 Citations (Scopus)


Ion current rectification with quartz nanopipette electrodes was investigated through the control of the surface charge. The presence and absence of a positively charged poly-L-lysine (PLL) coating resulted in the rectified current with opposite polarity. The results agreed with the theories developed for current-rectifying conical nanopores, suggesting the similar underlying mechanism among asymmetric nanostructure in general. This surface condition dependence can be used as the fundamental principle of multi-purpose real-time in vivo biosensors.

Original languageEnglish
Pages (from-to)2486-2492
Number of pages7
JournalNano Letters
Issue number11
Publication statusPublished - 2006 Nov
Externally publishedYes


ASJC Scopus subject areas

  • Materials Science(all)
  • Electronic, Optical and Magnetic Materials
  • Chemistry (miscellaneous)

Cite this

Umehara, S., Pourmand, N., Webb, C. D., Davis, R. W., Yasuda, K., & Karhanek, M. (2006). Current rectification with poly-L-lysine-coated quartz nanopipettes. Nano Letters, 6(11), 2486-2492.