Decarbonylative Methylation of Aromatic Esters by a Nickel Catalyst

Toshimasa Okita; Kei Muto; Junichiro Yamaguchi

doi:10.1021/acs.orglett.8b01233

Decarbonylative Methylation of Aromatic Esters by a Nickel Catalyst

Toshimasa Okita, Kei Muto, Junichiro Yamaguchi

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

A Ni-catalyzed decarbonylative methylation of aromatic esters was achieved using methylaluminums as methylating agents. Dimethylaluminum chlorides uniquely worked as the methyl source. Because of the Lewis acidity of aluminum reagents, less reactive alkyl esters could also undergo the present methylation. By controlling the Lewis acidity of aluminum reagents, a chemoselective decarbonylative cross-coupling between alkyl esters and phenyl esters was successful.

Original language	English
Pages (from-to)	3132-3135
Number of pages	4
Journal	Organic Letters
Volume	20
Issue number	10
DOIs	https://doi.org/10.1021/acs.orglett.8b01233
Publication status	Published - 2018 May 18

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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