Decarbonylative Methylation of Aromatic Esters by a Nickel Catalyst

Toshimasa Okita, Kei Muto, Junichiro Yamaguchi

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

A Ni-catalyzed decarbonylative methylation of aromatic esters was achieved using methylaluminums as methylating agents. Dimethylaluminum chlorides uniquely worked as the methyl source. Because of the Lewis acidity of aluminum reagents, less reactive alkyl esters could also undergo the present methylation. By controlling the Lewis acidity of aluminum reagents, a chemoselective decarbonylative cross-coupling between alkyl esters and phenyl esters was successful.

Original languageEnglish
Pages (from-to)3132-3135
Number of pages4
JournalOrganic Letters
Volume20
Issue number10
DOIs
Publication statusPublished - 2018 May 18

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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