Deployment of stent graft in an excessively higher position above the renal artery induces a flow channel to the aneurysm in chimney endovascular aortic aneurysm repair: an in vitro study

Kota Shukuzawa, Taku Akaoka, Mitsuo Umezu, Takao Ohki, Kiyotaka Iwasaki

    Research output: Contribution to journalArticle

    Abstract

    We aimed to investigate the influences of the sealing length above the renal artery (RA) on gutter formation, non-apposed regions between the aortic wall, stent graft (SG), and chimney graft and incidence of flow channel to the aneurysm in chimney endovascular aortic aneurysm repair (Ch-EVAR) using a juxtarenal abdominal aortic aneurysm model. Neck diameter and length of the silicone model were 24 and 4 mm, respectively. In double Ch-EVAR configuration using Advanta V12, 12 combinations were tested three times with two sizes [28.5 (20%-oversize) and 31 (30%-oversize) mm] of Excluder SG, three sealing lengths above the RA (10, 20, and 30 mm), and two deployment positions (anatomical and cross-leg). Gutter area, non-apposed region, and flow channels to the aneurysm were analyzed using micro-computed tomography. Average gutter area and non-apposed region of 30%-oversize SG were significantly smaller than those of 20%-oversize SG (p = 0.05). Furthermore, the non-apposed region of 30%-oversize SG with a 30-mm sealing length was significantly larger than that of the other sealing lengths. For 20%-oversize SGs, flow channel to the aneurysm was observed, except for the anatomical deployment with the sealing length of 10 mm. For 30%-oversize SGs, flow channel was absent, except for the SG with a 30-mm sealing length in both deployment positions. These flow channels were frequently formed through a valley space, existing in the lower unibody above the two limbs. Our data indicated that the optimal sealing length should be chosen in consideration of the device design difference due to the device diameter in Ch-EVAR.

    Original languageEnglish
    JournalJournal of Artificial Organs
    DOIs
    Publication statusAccepted/In press - 2019 Jan 1

    Fingerprint

    Chimneys
    Stents
    Aortic Aneurysm
    Renal Artery
    Channel flow
    Grafts
    Aneurysm
    Repair
    Transplants
    Equipment Design
    Abdominal Aortic Aneurysm
    Silicones
    In Vitro Techniques
    Tomography
    Leg
    Neck
    Extremities
    Equipment and Supplies
    Incidence

    Keywords

    • Chimney technique
    • Endovascular aortic repair
    • Gutter
    • In vitro
    • Juxtarenal aortic aneurysm

    ASJC Scopus subject areas

    • Medicine (miscellaneous)
    • Biomaterials
    • Biomedical Engineering
    • Cardiology and Cardiovascular Medicine

    Cite this

    @article{21c62ca64df14d2da5798cc936bf2c6d,
    title = "Deployment of stent graft in an excessively higher position above the renal artery induces a flow channel to the aneurysm in chimney endovascular aortic aneurysm repair: an in vitro study",
    abstract = "We aimed to investigate the influences of the sealing length above the renal artery (RA) on gutter formation, non-apposed regions between the aortic wall, stent graft (SG), and chimney graft and incidence of flow channel to the aneurysm in chimney endovascular aortic aneurysm repair (Ch-EVAR) using a juxtarenal abdominal aortic aneurysm model. Neck diameter and length of the silicone model were 24 and 4 mm, respectively. In double Ch-EVAR configuration using Advanta V12, 12 combinations were tested three times with two sizes [28.5 (20{\%}-oversize) and 31 (30{\%}-oversize) mm] of Excluder SG, three sealing lengths above the RA (10, 20, and 30 mm), and two deployment positions (anatomical and cross-leg). Gutter area, non-apposed region, and flow channels to the aneurysm were analyzed using micro-computed tomography. Average gutter area and non-apposed region of 30{\%}-oversize SG were significantly smaller than those of 20{\%}-oversize SG (p = 0.05). Furthermore, the non-apposed region of 30{\%}-oversize SG with a 30-mm sealing length was significantly larger than that of the other sealing lengths. For 20{\%}-oversize SGs, flow channel to the aneurysm was observed, except for the anatomical deployment with the sealing length of 10 mm. For 30{\%}-oversize SGs, flow channel was absent, except for the SG with a 30-mm sealing length in both deployment positions. These flow channels were frequently formed through a valley space, existing in the lower unibody above the two limbs. Our data indicated that the optimal sealing length should be chosen in consideration of the device design difference due to the device diameter in Ch-EVAR.",
    keywords = "Chimney technique, Endovascular aortic repair, Gutter, In vitro, Juxtarenal aortic aneurysm",
    author = "Kota Shukuzawa and Taku Akaoka and Mitsuo Umezu and Takao Ohki and Kiyotaka Iwasaki",
    year = "2019",
    month = "1",
    day = "1",
    doi = "10.1007/s10047-019-01090-x",
    language = "English",
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    TY - JOUR

    T1 - Deployment of stent graft in an excessively higher position above the renal artery induces a flow channel to the aneurysm in chimney endovascular aortic aneurysm repair

    T2 - an in vitro study

    AU - Shukuzawa, Kota

    AU - Akaoka, Taku

    AU - Umezu, Mitsuo

    AU - Ohki, Takao

    AU - Iwasaki, Kiyotaka

    PY - 2019/1/1

    Y1 - 2019/1/1

    N2 - We aimed to investigate the influences of the sealing length above the renal artery (RA) on gutter formation, non-apposed regions between the aortic wall, stent graft (SG), and chimney graft and incidence of flow channel to the aneurysm in chimney endovascular aortic aneurysm repair (Ch-EVAR) using a juxtarenal abdominal aortic aneurysm model. Neck diameter and length of the silicone model were 24 and 4 mm, respectively. In double Ch-EVAR configuration using Advanta V12, 12 combinations were tested three times with two sizes [28.5 (20%-oversize) and 31 (30%-oversize) mm] of Excluder SG, three sealing lengths above the RA (10, 20, and 30 mm), and two deployment positions (anatomical and cross-leg). Gutter area, non-apposed region, and flow channels to the aneurysm were analyzed using micro-computed tomography. Average gutter area and non-apposed region of 30%-oversize SG were significantly smaller than those of 20%-oversize SG (p = 0.05). Furthermore, the non-apposed region of 30%-oversize SG with a 30-mm sealing length was significantly larger than that of the other sealing lengths. For 20%-oversize SGs, flow channel to the aneurysm was observed, except for the anatomical deployment with the sealing length of 10 mm. For 30%-oversize SGs, flow channel was absent, except for the SG with a 30-mm sealing length in both deployment positions. These flow channels were frequently formed through a valley space, existing in the lower unibody above the two limbs. Our data indicated that the optimal sealing length should be chosen in consideration of the device design difference due to the device diameter in Ch-EVAR.

    AB - We aimed to investigate the influences of the sealing length above the renal artery (RA) on gutter formation, non-apposed regions between the aortic wall, stent graft (SG), and chimney graft and incidence of flow channel to the aneurysm in chimney endovascular aortic aneurysm repair (Ch-EVAR) using a juxtarenal abdominal aortic aneurysm model. Neck diameter and length of the silicone model were 24 and 4 mm, respectively. In double Ch-EVAR configuration using Advanta V12, 12 combinations were tested three times with two sizes [28.5 (20%-oversize) and 31 (30%-oversize) mm] of Excluder SG, three sealing lengths above the RA (10, 20, and 30 mm), and two deployment positions (anatomical and cross-leg). Gutter area, non-apposed region, and flow channels to the aneurysm were analyzed using micro-computed tomography. Average gutter area and non-apposed region of 30%-oversize SG were significantly smaller than those of 20%-oversize SG (p = 0.05). Furthermore, the non-apposed region of 30%-oversize SG with a 30-mm sealing length was significantly larger than that of the other sealing lengths. For 20%-oversize SGs, flow channel to the aneurysm was observed, except for the anatomical deployment with the sealing length of 10 mm. For 30%-oversize SGs, flow channel was absent, except for the SG with a 30-mm sealing length in both deployment positions. These flow channels were frequently formed through a valley space, existing in the lower unibody above the two limbs. Our data indicated that the optimal sealing length should be chosen in consideration of the device design difference due to the device diameter in Ch-EVAR.

    KW - Chimney technique

    KW - Endovascular aortic repair

    KW - Gutter

    KW - In vitro

    KW - Juxtarenal aortic aneurysm

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    JF - Journal of Artificial Organs

    SN - 1434-7229

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