In nuclear power plants, fluid structure interactions (FSI) occurring in component systems can cause excessive forces or stresses to the structures resulting in mechanical damages that may eventually threaten the structural integrity. FSI in the guidelines includes flow-induced vibration, water hammer, and pipewhip. It can also include movement, deformation, or fracture of equipments by tsunami etc. They can be issues of design and maintenance. Authors cannot find complete guidelines to correspond to the FSI phenomena which can be important in the design and maintenance of nuclear power plants. Based on the background, International Atomic Energy Agency (IAEA) has drafted guidelines on FSI. This paper summarizes general description of FSI as well as design and maintenance against FSI.