Development of a brain PET system, PET-Hat: A wearable PET system for brain research

Seiichi Yamamoto*, Manabu Honda, Tutomu Oohashi, Keiji Shimizu, Michio Senda

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

62 Citations (Scopus)

Abstract

Brain functional studies using PET have advantages over fMRI in some areas such as auditory research in part because PET systems produce no acoustic noise during acquisition. However commercially available PET systems are designed for whole body studies and are not optimized for brain functional studies. We developed a low cost, small, wearable brain PET system named PET-Hat dedicated for brain imaging. It employs double counter-balanced systems for mechanical supports of the detector ring while allowing the subject some freedom of motion. The motion enables subject to be measured in the sitting position and move relatively freely with the PET during acquisition. The detector consists of a Gd2SiO5 (GSO) block, a tapered light guide and a flat panel photomultiplier tube (FP-PMT). Two types of GSO are used for depth-of-interaction (DOI) separation allowing the use of a small ring diameter without resolution degradation. The tapered light guide allows the use of larger GSO blocks with fewer FP-PMTs. Sixteen detector blocks are arranged in a 280 mm diameter ring. Transaxial and axial field-of-view (FOV) are 20 cm and 4.8 cm, respectively. Energy resolution of the block detectors was ∼ 15% full width at half maximum (FWHM) and timing resolution was ∼ 4.6 ns FWHM. Transaxial resolution and axial resolution at the center of the FOV were ∼ 4.0 mm FWHM and ∼ 3.5 mm FWHM, respectively. Sensitivity was 0.7% at the center of the axial FOV. Scatter fraction was ∼ 0.6. Hoffman brain phantom images were successfully obtained. We conclude that the PET-Hat is a promising, low cost, small, wearable brain PET system for brain functional studies.

Original languageEnglish
Article number5741875
Pages (from-to)668-673
Number of pages6
JournalIEEE Transactions on Nuclear Science
Volume58
Issue number3 PART 1
DOIs
Publication statusPublished - 2011 Jun
Externally publishedYes

Keywords

  • Brain
  • GSO
  • PET
  • PSPMT
  • wearable

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Nuclear Energy and Engineering
  • Electrical and Electronic Engineering

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