Development of a compact artificial gill using concentrated hemoglobin solution as the oxygen carrier

Ken Ichi Nagase, Fukashi Kohori, Kiyotaka Sakai

    Research output: Contribution to journalArticle

    8 Citations (Scopus)

    Abstract

    An artificial gill was developed using a concentrated hemoglobin solution containing inositol hexaphosphate (IHP), as the oxygen carrier solution, with the oxygen affinity controlled by temperature. Oxygen dissolved in sea water is first taken up from water to the oxygen carrier solution at 293K. The oxygen carrier solution is then heated and the oxygen is released from the oxygen carrier solution to expired air at 310K. The enhancement factors of the oxygen carrier solution that indicate its performance were obtained from the oxygen uptake rate and oxygen release rate. The values were approximately 3 at oxygen uptake and 16 at oxygen release. The scale-up for a human being at rest was estimated using these values, and the optimal operating condition was determined. The required membrane surface area for a human being is 63.8m2. The oxygen partial pressure of inspiration is 20.7kPa, adequate for the respiration. These indicate the feasibility of a compact and portable artificial gill device.

    Original languageEnglish
    Pages (from-to)281-292
    Number of pages12
    JournalJournal of Membrane Science
    Volume215
    Issue number1-2
    DOIs
    Publication statusPublished - 2003 Apr 15

    Fingerprint

    Hemoglobin
    hemoglobin
    Hemoglobins
    Oxygen
    oxygen
    expired air
    inositols
    Phytic Acid
    inspiration
    Water
    sea water
    Partial Pressure
    Dissolved oxygen
    respiration
    Seawater
    Partial pressure
    partial pressure
    affinity
    Respiration
    Air

    Keywords

    • Facilitated transport
    • Fiber membranes
    • Gas separation modules
    • Oxygen transfer

    ASJC Scopus subject areas

    • Filtration and Separation
    • Polymers and Plastics

    Cite this

    Development of a compact artificial gill using concentrated hemoglobin solution as the oxygen carrier. / Nagase, Ken Ichi; Kohori, Fukashi; Sakai, Kiyotaka.

    In: Journal of Membrane Science, Vol. 215, No. 1-2, 15.04.2003, p. 281-292.

    Research output: Contribution to journalArticle

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