Development of a compact scintillator-based high-resolution Compton camera for molecular imaging

A. Kishimoto, Jun Kataoka, A. Koide, K. Sueoka, Y. Iwamoto, T. Taya, S. Ohsuka

    Research output: Contribution to journalArticle

    15 Citations (Scopus)

    Abstract

    The Compton camera, which shows gamma-ray distribution utilizing the kinematics of Compton scattering, is a promising detector capable of imaging across a wide range of energy. In this study, we aim to construct a small-animal molecular imaging system in a wide energy range by using the Compton camera. We developed a compact medical Compton camera based on a Ce-doped Gd3Al2Ga3O12 (Ce:GAGG) scintillator and multi-pixel photon counter (MPPC). A basic performance confirmed that for 662keV, the typical energy resolution was 7.4% (FWHM) and the angular resolution was 4.5° (FWHM). We then used the medical Compton camera to conduct imaging experiments based on a 3-D imaging reconstruction algorithm using the multi-angle data acquisition method. The result confirmed that for a 137Cs point source at a distance of 4cm, the image had a spatial resolution of 3.1mm (FWHM). Furthermore, we succeeded in producing 3-D multi-color image of different simultaneous energy sources (22Na [511keV], 137Cs [662keV], and 54Mn [834keV]).

    Keywords

    • Compton camera
    • Depth of interaction

    ASJC Scopus subject areas

    • Instrumentation
    • Nuclear and High Energy Physics

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