Development of a polymer bileaflet valve to realize a low-cost pulsatile blood pump

Kiyotaka Iwasaki, Mitsuo Umezu, Kazuo Iijima, Akira Inoue, Kou Imachi, Chun Xiu Ye

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    The final goal of this study is to realize a low-cost pulsatile blood pump especially for patients with acute heart failure or postoperative low cardiac output syndrome. In support of the pump, two types of polymer bileaflet valves with different configuration of the valve seats were developed. Influence of the leaflet thickness on the hydrodynamics of the prototype was preliminarily investigated among 70 μm, 100 μm, and 150 μm. As to the valves with the thinner leaflets, buckling of the leaflets was observed, which induced a large amount of regurgitation at valve closure. However, by thickening the leaflet to 150 μm, the mean flow of the prototype and the second model could be successfully comparable to the Medtronic-Hall valve. Moreover, accelerated fatigue tests showed that reinforcement of the valve seat with the additional spokes in the second model extended the durability by four times as compared with the prototype, equivalent to an in vivo duration of over one month.

    Original languageEnglish
    Pages (from-to)78-83
    Number of pages6
    JournalArtificial Organs
    Volume27
    Issue number1
    DOIs
    Publication statusPublished - 2003

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    Keywords

    • Bileaflet valve
    • Disposable
    • Low cost
    • Polymer valve
    • Pulsatile blood pump

    ASJC Scopus subject areas

    • Biophysics

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