Development of an all-fluoroplastic microfluidic device applied as a nanoliter sample injector

Takaomi Sato, Kentaro Kawai, Masaki Kanai, Shuichi Shoji

    Research output: Contribution to journalArticle

    5 Citations (Scopus)

    Abstract

    A method was developed to fabricate an all-fluoroplastic microfluidic device using NEOFLON EFEP, a new fluoroplastic material. The device was successfully used as a nanoliter sample injector, which is very useful for various biological assays and chemical syntheses. The advantages of NEOFLON are that it is easily structured, it bonds at low temperatures, and it has chemical/physical robustness. NEOFLON microchannels 5μm in width and 5 μm in height were successfully fabricated for the prototype sample injector. The injector enabled the sample injection and metering of a 1.9 nL sample with less than 2% volume change. This suggests that the NEOFLON flow device is capable of the precise fluidic handling of a few nanoliter samples in volume.

    Original languageEnglish
    JournalJapanese Journal of Applied Physics
    Volume48
    Issue number6 PART 2
    DOIs
    Publication statusPublished - 2009 Jun

    Fingerprint

    fluoropolymers
    microfluidic devices
    injectors
    Microfluidics
    Fluidics
    Microchannels
    Assays
    fluidics
    microchannels
    Temperature
    prototypes
    injection
    synthesis

    ASJC Scopus subject areas

    • Engineering(all)
    • Physics and Astronomy(all)

    Cite this

    Development of an all-fluoroplastic microfluidic device applied as a nanoliter sample injector. / Sato, Takaomi; Kawai, Kentaro; Kanai, Masaki; Shoji, Shuichi.

    In: Japanese Journal of Applied Physics, Vol. 48, No. 6 PART 2, 06.2009.

    Research output: Contribution to journalArticle

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