Development of an all-fluoroplastic microfluidic device applied as a nanoliter sample injector

Takaomi Sato, Kentaro Kawai, Masaki Kanai, Shuichi Shoji

Research output: Contribution to journalArticle

5 Citations (Scopus)


A method was developed to fabricate an all-fluoroplastic microfluidic device using NEOFLON EFEP, a new fluoroplastic material. The device was successfully used as a nanoliter sample injector, which is very useful for various biological assays and chemical syntheses. The advantages of NEOFLON are that it is easily structured, it bonds at low temperatures, and it has chemical/physical robustness. NEOFLON microchannels 5μm in width and 5 μm in height were successfully fabricated for the prototype sample injector. The injector enabled the sample injection and metering of a 1.9 nL sample with less than 2% volume change. This suggests that the NEOFLON flow device is capable of the precise fluidic handling of a few nanoliter samples in volume.

Original languageEnglish
Pages (from-to)06FJ031-06FJ034
JournalJapanese journal of applied physics
Issue number6 PART 2
Publication statusPublished - 2009 Jun 1


ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this