Transillumination image becomes blurred significantly by the strong scattering of biological tissue. Analyzing the beam wave propagation inside the scattering medium, we have shown possibility to improve the transillumination image in the beam-incident case. However, uniformity of the background was still insufficient. In a plane-wave incident case, the original image is effectively restored by inverting the transillumination image before the PSF deconvolution. In this paper, we newly introduced this principle to the case with inhomogeneous light beam illumination. We combined the background homogenization and the scattering suppression processes into a simple equation. The effectiveness of this technique was confirmed in experiments.
|Journal||Transactions of Japanese Society for Medical and Biological Engineering|
|Publication status||Published - 2014 Aug 17|
- Beam-wave propagation
- Point spread function (PSF)
- Transillumination imaging
ASJC Scopus subject areas
- Biomedical Engineering