Differences in muscle O2 dynamics during treadmill exercise between aerobic capacity-matched overweight and normal-weight adults

Shun Takagi, Ryotaro Kime, Taishi Midorikawa, Masatsugu Niwayama, Shizuo Sakamoto, Toshihito Katsumura

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The aim of this study was to compare muscle O2 dynamics during exercise between aerobic capacity-matched overweight and normal-weight adults. Overweight women (OW, n = 9) and normal-weight women (NW, n = 14) performed graded treadmill exercise until exhaustion. Muscle O2 saturation (SmO2) and relative changes from rest in deoxygenated hemoglobin concentration (∆deoxy-Hb) and total hemoglobin concentration (∆total-Hb) were monitored continuously at gastrocnemius medialis muscle by near infrared spatial resolved spectroscopy. Significantly higher SmO2 and lower ∆deoxy-Hb and ∆total-Hb were observed in OW compared with NW. Pulmonary O2 uptake (VO2) normalized by fat-free mass was matched between groups. In both groups, peak VO2 was significantly correlated with change in SmO2 and ∆deoxy-Hb. Our findings suggest that both muscle blood volume and deoxygenation were lower in overweight adults, compared to aerobic capacity-matched normal-weight adults. Moreover, lowered muscle O2 extraction was related to peak VO2 in overweight adults, as well as in normal-weight adults.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages223-229
Number of pages7
DOIs
Publication statusPublished - 2020

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1232
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Blood volume
  • Muscle O extraction
  • Near infrared spectroscopy
  • Regional difference
  • Women

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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    Takagi, S., Kime, R., Midorikawa, T., Niwayama, M., Sakamoto, S., & Katsumura, T. (2020). Differences in muscle O2 dynamics during treadmill exercise between aerobic capacity-matched overweight and normal-weight adults. In Advances in Experimental Medicine and Biology (pp. 223-229). (Advances in Experimental Medicine and Biology; Vol. 1232). Springer. https://doi.org/10.1007/978-3-030-34461-0_28