Differences in recruitment properties of the corticospinal pathway between lengthening and shortening contractions in human soleus muscle

Hirofumi Sekiguchi, Kimitaka Nakazawa, Shuji Suzuki

    Research output: Contribution to journalArticle

    33 Citations (Scopus)

    Abstract

    The purpose of this study was to investigate how the recruitment properties of the corticospinal pathway are modulated in the soleus muscle of the lower limb during lengthening (LEN) and shortening (SHO) contractions by comparing the shape of the input-output (I/O) relation of the corticospinal pathway. To this end, we investigated the relationship between various stimulus intensities applied via transcranial magnetic stimulation and the size of motor-evoked potentials in 14 healthy subjects during voluntary plantarflexion and dorsiflexion (active lengthening) with a similar background activity (BGA) level. The shape of this relationship was sigmoidal and was characterized by a plateau value, maximum slope and threshold. The plateau value was clearly lower during LEN contractions than during SHO contractions. Likewise, the maximum slope was lower during LEN contractions. However, the threshold did not differ significantly between the two tasks. Since the plateau value and the maximum slope clearly differed between LEN and SHO contractions despite the similarity of their BGA levels, the central nervous system appears to have a different activation strategy for each of these tasks. Namely, the relative balance between excitatory and inhibitory components of the corticospinal volleys, as well as the subliminal fringe of the corticospinal pathway, were reduced during LEN contractions compared with SHO contractions. These strategies may help to avoid reflexive contractions brought about by higher discharge of muscle spindles and enable fine motor actions in voluntary lengthening contractions.

    Original languageEnglish
    Pages (from-to)169-179
    Number of pages11
    JournalBrain Research
    Volume977
    Issue number2
    DOIs
    Publication statusPublished - 2003 Jul 11

    Fingerprint

    Muscle Spindles
    Motor Evoked Potentials
    Transcranial Magnetic Stimulation
    Lower Extremity
    Healthy Volunteers
    Skeletal Muscle
    Central Nervous System

    Keywords

    • Corticospinal pathway
    • Input-output properties
    • Lengthening contraction
    • Transcranial magnetic stimulation

    ASJC Scopus subject areas

    • Neuroscience(all)

    Cite this

    Differences in recruitment properties of the corticospinal pathway between lengthening and shortening contractions in human soleus muscle. / Sekiguchi, Hirofumi; Nakazawa, Kimitaka; Suzuki, Shuji.

    In: Brain Research, Vol. 977, No. 2, 11.07.2003, p. 169-179.

    Research output: Contribution to journalArticle

    Sekiguchi, Hirofumi ; Nakazawa, Kimitaka ; Suzuki, Shuji. / Differences in recruitment properties of the corticospinal pathway between lengthening and shortening contractions in human soleus muscle. In: Brain Research. 2003 ; Vol. 977, No. 2. pp. 169-179.
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