Differential modulation in human primary and secondary somatosensory cortices during the preparatory period of self-initiated finger movement

Toshiaki Wasaka, Hiroki Nakata, Kosuke Akatsuka, Tetsuo Kida, Koji Inui, Ryusuke Kakigi

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

To elucidate the mechanisms underlying sensorimotor integration, we investigated modulation in the primary (SI) and secondary (SII) somatosensory cortices during the preparatory period of a self-initiated finger extension. Electrical stimulation of the right median nerve was applied continuously, while the subjects performed a self-initiated finger extension and were instructed not to pay attention to the stimulation. The preparatory period was divided into five sub-periods from the onset of the electromyogram to 3000 ms before movement and the magnetoencephalogram signals following stimulation in each sub-period were averaged. Multiple source analysis indicated that the equivalent current dipoles (ECDs) were located in SI and bilateral SII. Although the ECD moment for N20m (the upward deflection peaking at around 20 ms) was not significantly changed, that for P30m (the downward deflection peaking at around 30 m) was significantly smaller in the 0- to -500-ms sub-period than the -2000- to -3000-ms sub-period. As for SII, the ECD moment for the SII ipsilateral to movement showed no significant change, while that for the contralateral SII was significantly larger in the 0- to -500-ms sub-period than the -1500- to -2000-ms or -2000- to -3000-ms sub-period. The opposite effects of movement on SI and SII cortices indicated that these cortical areas play a different role in the function of the sensorimotor integration and are affected differently by the centrifugal process.

Original languageEnglish
Pages (from-to)1239-1247
Number of pages9
JournalEuropean Journal of Neuroscience
Volume22
Issue number5
DOIs
Publication statusPublished - 2005 Sep

Fingerprint

Somatosensory Cortex
Fingers
Median Nerve
Electromyography
Electric Stimulation

Keywords

  • Centrifugal
  • Magnetoencephalography
  • Self-initiated movement
  • Somatosensory cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Differential modulation in human primary and secondary somatosensory cortices during the preparatory period of self-initiated finger movement. / Wasaka, Toshiaki; Nakata, Hiroki; Akatsuka, Kosuke; Kida, Tetsuo; Inui, Koji; Kakigi, Ryusuke.

In: European Journal of Neuroscience, Vol. 22, No. 5, 09.2005, p. 1239-1247.

Research output: Contribution to journalArticle

Wasaka, Toshiaki ; Nakata, Hiroki ; Akatsuka, Kosuke ; Kida, Tetsuo ; Inui, Koji ; Kakigi, Ryusuke. / Differential modulation in human primary and secondary somatosensory cortices during the preparatory period of self-initiated finger movement. In: European Journal of Neuroscience. 2005 ; Vol. 22, No. 5. pp. 1239-1247.
@article{360e79eed7954818abb6ad0f908d6b94,
title = "Differential modulation in human primary and secondary somatosensory cortices during the preparatory period of self-initiated finger movement",
abstract = "To elucidate the mechanisms underlying sensorimotor integration, we investigated modulation in the primary (SI) and secondary (SII) somatosensory cortices during the preparatory period of a self-initiated finger extension. Electrical stimulation of the right median nerve was applied continuously, while the subjects performed a self-initiated finger extension and were instructed not to pay attention to the stimulation. The preparatory period was divided into five sub-periods from the onset of the electromyogram to 3000 ms before movement and the magnetoencephalogram signals following stimulation in each sub-period were averaged. Multiple source analysis indicated that the equivalent current dipoles (ECDs) were located in SI and bilateral SII. Although the ECD moment for N20m (the upward deflection peaking at around 20 ms) was not significantly changed, that for P30m (the downward deflection peaking at around 30 m) was significantly smaller in the 0- to -500-ms sub-period than the -2000- to -3000-ms sub-period. As for SII, the ECD moment for the SII ipsilateral to movement showed no significant change, while that for the contralateral SII was significantly larger in the 0- to -500-ms sub-period than the -1500- to -2000-ms or -2000- to -3000-ms sub-period. The opposite effects of movement on SI and SII cortices indicated that these cortical areas play a different role in the function of the sensorimotor integration and are affected differently by the centrifugal process.",
keywords = "Centrifugal, Magnetoencephalography, Self-initiated movement, Somatosensory cortex",
author = "Toshiaki Wasaka and Hiroki Nakata and Kosuke Akatsuka and Tetsuo Kida and Koji Inui and Ryusuke Kakigi",
year = "2005",
month = "9",
doi = "10.1111/j.1460-9568.2005.04289.x",
language = "English",
volume = "22",
pages = "1239--1247",
journal = "European Journal of Neuroscience",
issn = "0953-816X",
publisher = "Wiley-Blackwell",
number = "5",

}

TY - JOUR

T1 - Differential modulation in human primary and secondary somatosensory cortices during the preparatory period of self-initiated finger movement

AU - Wasaka, Toshiaki

AU - Nakata, Hiroki

AU - Akatsuka, Kosuke

AU - Kida, Tetsuo

AU - Inui, Koji

AU - Kakigi, Ryusuke

PY - 2005/9

Y1 - 2005/9

N2 - To elucidate the mechanisms underlying sensorimotor integration, we investigated modulation in the primary (SI) and secondary (SII) somatosensory cortices during the preparatory period of a self-initiated finger extension. Electrical stimulation of the right median nerve was applied continuously, while the subjects performed a self-initiated finger extension and were instructed not to pay attention to the stimulation. The preparatory period was divided into five sub-periods from the onset of the electromyogram to 3000 ms before movement and the magnetoencephalogram signals following stimulation in each sub-period were averaged. Multiple source analysis indicated that the equivalent current dipoles (ECDs) were located in SI and bilateral SII. Although the ECD moment for N20m (the upward deflection peaking at around 20 ms) was not significantly changed, that for P30m (the downward deflection peaking at around 30 m) was significantly smaller in the 0- to -500-ms sub-period than the -2000- to -3000-ms sub-period. As for SII, the ECD moment for the SII ipsilateral to movement showed no significant change, while that for the contralateral SII was significantly larger in the 0- to -500-ms sub-period than the -1500- to -2000-ms or -2000- to -3000-ms sub-period. The opposite effects of movement on SI and SII cortices indicated that these cortical areas play a different role in the function of the sensorimotor integration and are affected differently by the centrifugal process.

AB - To elucidate the mechanisms underlying sensorimotor integration, we investigated modulation in the primary (SI) and secondary (SII) somatosensory cortices during the preparatory period of a self-initiated finger extension. Electrical stimulation of the right median nerve was applied continuously, while the subjects performed a self-initiated finger extension and were instructed not to pay attention to the stimulation. The preparatory period was divided into five sub-periods from the onset of the electromyogram to 3000 ms before movement and the magnetoencephalogram signals following stimulation in each sub-period were averaged. Multiple source analysis indicated that the equivalent current dipoles (ECDs) were located in SI and bilateral SII. Although the ECD moment for N20m (the upward deflection peaking at around 20 ms) was not significantly changed, that for P30m (the downward deflection peaking at around 30 m) was significantly smaller in the 0- to -500-ms sub-period than the -2000- to -3000-ms sub-period. As for SII, the ECD moment for the SII ipsilateral to movement showed no significant change, while that for the contralateral SII was significantly larger in the 0- to -500-ms sub-period than the -1500- to -2000-ms or -2000- to -3000-ms sub-period. The opposite effects of movement on SI and SII cortices indicated that these cortical areas play a different role in the function of the sensorimotor integration and are affected differently by the centrifugal process.

KW - Centrifugal

KW - Magnetoencephalography

KW - Self-initiated movement

KW - Somatosensory cortex

UR - http://www.scopus.com/inward/record.url?scp=25844490524&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=25844490524&partnerID=8YFLogxK

U2 - 10.1111/j.1460-9568.2005.04289.x

DO - 10.1111/j.1460-9568.2005.04289.x

M3 - Article

C2 - 16176367

AN - SCOPUS:25844490524

VL - 22

SP - 1239

EP - 1247

JO - European Journal of Neuroscience

JF - European Journal of Neuroscience

SN - 0953-816X

IS - 5

ER -