Abstract
(Chemical Equation Presented) Regioselective alkenylation and alkylation of 2-pyridone derivatives are achieved through inter- and intramolecular insertion of alkynes, 1,3-dienes, and alkenes into the C(6)-H bond by nickel/AlMe 3 catalysis. Coordination of the heterocycles to the Lewis acid cocatalyst through their basic carbonyl oxygen is considered to be responsible for the regioselective activation of the C-H bonds, probably through oxidative addition to nickel(0).
Original language | English |
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Pages (from-to) | 15996-15997 |
Number of pages | 2 |
Journal | Journal of the American Chemical Society |
Volume | 131 |
Issue number | 44 |
DOIs | |
Publication status | Published - 2009 Nov 27 |
Externally published | Yes |
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
- Biochemistry
- Colloid and Surface Chemistry