Direct immobilization of DNA on partially functionalized diamond surface

Jung Hoon Yang, Kwang Soup Song, Shouma Kuga, Hiroshi Kawarada

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Amino groups were functionalized directly on the diamond surface after treating oxidation and fluorination for detection of DNAs, respectively. For simple process, immobilization of probe DNAs was carried out directly on the partially aminated diamond without linker molecules. After fabricating micropattemed diamond, specific hybridization with Cy-5 labeled target DNA at a concentration of 100 nM could be clearly detected on H-terminated, partially O-terminated, and partially F-terminated diamonds, respectively. The hybridization intensities determined by epifluorescence microscopy were compared and analyzed.

Original languageEnglish
Title of host publicationMaterials Research Society Symposium Proceedings
PublisherMaterials Research Society
Pages220-227
Number of pages8
ISBN (Print)9781604234060
DOIs
Publication statusPublished - 2006 Jan 1
Event2006 MRS Fall Meeting - Boston, MA, United States
Duration: 2006 Nov 272006 Nov 30

Publication series

NameMaterials Research Society Symposium Proceedings
Volume950
ISSN (Print)0272-9172

Other

Other2006 MRS Fall Meeting
CountryUnited States
CityBoston, MA
Period06/11/2706/11/30

ASJC Scopus subject areas

  • Materials Science(all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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  • Cite this

    Yang, J. H., Song, K. S., Kuga, S., & Kawarada, H. (2006). Direct immobilization of DNA on partially functionalized diamond surface. In Materials Research Society Symposium Proceedings (pp. 220-227). (Materials Research Society Symposium Proceedings; Vol. 950). Materials Research Society. https://doi.org/10.1557/proc-0950-d04-51