Direct proline catalyzed asymmetric α-aminooxylation of aldehydes

Yujiro Hayashi, Junichiro Yamaguchi, Kazuhiro Hibino, Mitsuru Shoji

Research output: Contribution to journalArticle

294 Citations (Scopus)

Abstract

The direct catalytic enantioselective α-aminooxylation of aldehydes has been developed using nitrosobenzene as the oxygen source and L-proline as catalyst, affording versatile α-aminooxylated aldehydes in high yield with excellent enantioselectivities.

Original languageEnglish
Pages (from-to)8293-8296
Number of pages4
JournalTetrahedron Letters
Volume44
Issue number45
DOIs
Publication statusPublished - 2003 Nov 3

Keywords

  • Asymmetric reaction
  • Catalytic reaction
  • Organocatalyst
  • Proline
  • α-aminooxylation

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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