Direct proline-catalyzed asymmetric α-aminoxylation of ketones

Yujiro Hayashi, Junichiro Yamaguchi, Tatsunobu Sumiya, Mitsuru Shoji

Research output: Contribution to journalArticle

251 Citations (Scopus)

Abstract

Nitrosobenzene is the oxygen source in the direct catalytic enantioselective α-aminoxylation of ketones catalyzed by L-proline [Eq. (1)]. Versatile α-aminoxylated ketones are obtained in high yield and with excellent enantioselectivities.

Original languageEnglish
Pages (from-to)1112-1115
Number of pages4
JournalAngewandte Chemie - International Edition
Volume43
Issue number9
DOIs
Publication statusPublished - 2004 Feb 20
Externally publishedYes

Fingerprint

Ketones
Proline
Enantioselectivity
Oxygen
nitrosobenzene

Keywords

  • Asymmetric catalysis
  • Ketones
  • Oxidation
  • Proline

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Direct proline-catalyzed asymmetric α-aminoxylation of ketones. / Hayashi, Yujiro; Yamaguchi, Junichiro; Sumiya, Tatsunobu; Shoji, Mitsuru.

In: Angewandte Chemie - International Edition, Vol. 43, No. 9, 20.02.2004, p. 1112-1115.

Research output: Contribution to journalArticle

Hayashi, Yujiro ; Yamaguchi, Junichiro ; Sumiya, Tatsunobu ; Shoji, Mitsuru. / Direct proline-catalyzed asymmetric α-aminoxylation of ketones. In: Angewandte Chemie - International Edition. 2004 ; Vol. 43, No. 9. pp. 1112-1115.
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