Discovery of luminescence of water during radiation irradiation and application for medical physics

Seiichi Yamamoto*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)


Optical imaging detecting Cerenkov-light is a promising approach for molecular imaging or radiation therapy, but it was not yet conducted for proton therapy because light was not thought to be produced with the energy ranges because they are lower than Cerenkov-light threshold. Contrary to this consensus, our research group found that luminescence was emitted from water during proton-beam irradiation. The luminescence images of water phantoms showed clear Bragg peak, and the measured proton ranges from the images were almost the same as those obtained with an ionization chamber. The luminescence was also observed for carbon-ion and low energy X-ray photons.

Original languageEnglish
Title of host publicationMolecular-Guided Surgery
Subtitle of host publicationMolecules, Devices, and Applications III
EditorsSylvain Gioux, Brian W. Pogue
ISBN (Electronic)9781510605398
Publication statusPublished - 2017
Externally publishedYes
EventMolecular-Guided Surgery: Molecules, Devices, and Applications III - San Francisco, United States
Duration: 2017 Jan 282017 Jan 30

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceMolecular-Guided Surgery: Molecules, Devices, and Applications III
Country/TerritoryUnited States
CitySan Francisco


  • Carbon-ion beam
  • Lower than Cerenkov-light threshold
  • Luminescence of water
  • Proton-beam
  • X-ray

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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