Distribution and structure of lymphatics in the human diaphragmatic and mediastinal pleura

S. Masada, Y. Nakamura, H. Nakamura, Norihiko Kawate, N. Kawate, M. Noguchi, S. Uchino, Y. Ebihara, C. Konaka, H. Kato

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Investigation of the distribution pattern and structure of lymphatics in the parietal pleura is indispensable to clarify poor prognostic factors of lung cancer such as pleural dissemination and malignant pleural effusion. Using cadavers we investigated by means of the distribution patients of lymphatics in detail using an enzymehistochemical technique and their structure using light and both scanning and transmission electron microscopy. Initially lymphatics arose from connective tissue just below mesothelial tissue and though their density varied in different portions, they immediately interconnected form a plexus. These lymphatics gradually ran into deep layers of the pleura and in the muscular part of the diaphragm connected with conduit lymphatics, which were distributed in parallel to the muscle fibers. The conduit lymphatic vessels drained into several groups in the diaphragmatic pleura; (1)towards the lower sternal portion; (2) to the boundary adjoining the intercostal pleura; (3) to the junction of vertebrae and ribs: (4) to the aortic hiatus; (5) to the esophageal hiatus. Furthermore, in the mediastinal pleura there was drainage into; (1) the upper and lower portions of the sternum; (2) the inferior anterior adjoining the pericardial sac; (3) the hilum of the lung; (4) the aortic hiatus; (5) the esophageal hiatus. Using scanning electron microscopy few stoma were observed in the middle of the muscular portion of the diaphragmatic pleura.

Original languageEnglish
Pages (from-to)875-882
Number of pages8
JournalJapanese Journal of Lung Cancer
Volume35
Issue number7
Publication statusPublished - 1995
Externally publishedYes

Fingerprint

Pleura
Malignant Pleural Effusion
Scanning Transmission Electron Microscopy
Sternum
Lymphatic Vessels
Pericardium
Ribs
Diaphragm
Cadaver
Connective Tissue
Electron Scanning Microscopy
Drainage
Lung Neoplasms
Spine
Epithelium
Light
Muscles
Lung

Keywords

  • Electron microscope
  • Enzyme histochemistry
  • Lymphatics
  • Parietal pleura
  • Stoma

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

Cite this

Masada, S., Nakamura, Y., Nakamura, H., Kawate, N., Kawate, N., Noguchi, M., ... Kato, H. (1995). Distribution and structure of lymphatics in the human diaphragmatic and mediastinal pleura. Japanese Journal of Lung Cancer, 35(7), 875-882.

Distribution and structure of lymphatics in the human diaphragmatic and mediastinal pleura. / Masada, S.; Nakamura, Y.; Nakamura, H.; Kawate, Norihiko; Kawate, N.; Noguchi, M.; Uchino, S.; Ebihara, Y.; Konaka, C.; Kato, H.

In: Japanese Journal of Lung Cancer, Vol. 35, No. 7, 1995, p. 875-882.

Research output: Contribution to journalArticle

Masada, S, Nakamura, Y, Nakamura, H, Kawate, N, Kawate, N, Noguchi, M, Uchino, S, Ebihara, Y, Konaka, C & Kato, H 1995, 'Distribution and structure of lymphatics in the human diaphragmatic and mediastinal pleura', Japanese Journal of Lung Cancer, vol. 35, no. 7, pp. 875-882.
Masada, S. ; Nakamura, Y. ; Nakamura, H. ; Kawate, Norihiko ; Kawate, N. ; Noguchi, M. ; Uchino, S. ; Ebihara, Y. ; Konaka, C. ; Kato, H. / Distribution and structure of lymphatics in the human diaphragmatic and mediastinal pleura. In: Japanese Journal of Lung Cancer. 1995 ; Vol. 35, No. 7. pp. 875-882.
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