Distribution of parvalbumin immunoreactivity in the human brain

Toshio Ohshima, Toyoshi Endo, Toshimasa Onaya

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

The cellular distribution of parvalbumin-like immunoreactivity (PA-LI) in the human brain was investigated by peroxidase-antiperoxidase methods using antiserum to rat skeletal muscle parvalbumin. PA-LI was present in non-pyramidal neurons of the cerebral cortices, stellate cells, basket cells and Purkinje cells in cerebellar cortices, and neurons of some nuclei in human brain stem; the distribution of PA-LI in human brain was very similar to that in rat brain. These results indicate that PA-LI is widely distributed in a specific subpopulation of neurons of the human brain.

Original languageEnglish
Pages (from-to)320-322
Number of pages3
JournalJournal of Neurology
Volume238
Issue number6
DOIs
Publication statusPublished - 1991 Sep
Externally publishedYes

Fingerprint

Parvalbumins
Brain
Neurons
Cerebellar Cortex
Purkinje Cells
Cerebral Cortex
Peroxidase
Brain Stem
Immune Sera
Skeletal Muscle

Keywords

  • Calcium-binding protein
  • Immunohistochemistry
  • Parvalbumin

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Distribution of parvalbumin immunoreactivity in the human brain. / Ohshima, Toshio; Endo, Toyoshi; Onaya, Toshimasa.

In: Journal of Neurology, Vol. 238, No. 6, 09.1991, p. 320-322.

Research output: Contribution to journalArticle

Ohshima, Toshio ; Endo, Toyoshi ; Onaya, Toshimasa. / Distribution of parvalbumin immunoreactivity in the human brain. In: Journal of Neurology. 1991 ; Vol. 238, No. 6. pp. 320-322.
@article{a9676b2fff8e43ab98610c114656e12f,
title = "Distribution of parvalbumin immunoreactivity in the human brain",
abstract = "The cellular distribution of parvalbumin-like immunoreactivity (PA-LI) in the human brain was investigated by peroxidase-antiperoxidase methods using antiserum to rat skeletal muscle parvalbumin. PA-LI was present in non-pyramidal neurons of the cerebral cortices, stellate cells, basket cells and Purkinje cells in cerebellar cortices, and neurons of some nuclei in human brain stem; the distribution of PA-LI in human brain was very similar to that in rat brain. These results indicate that PA-LI is widely distributed in a specific subpopulation of neurons of the human brain.",
keywords = "Calcium-binding protein, Immunohistochemistry, Parvalbumin",
author = "Toshio Ohshima and Toyoshi Endo and Toshimasa Onaya",
year = "1991",
month = "9",
doi = "10.1007/BF00315329",
language = "English",
volume = "238",
pages = "320--322",
journal = "Journal of Neurology",
issn = "0340-5354",
publisher = "D. Steinkopff-Verlag",
number = "6",

}

TY - JOUR

T1 - Distribution of parvalbumin immunoreactivity in the human brain

AU - Ohshima, Toshio

AU - Endo, Toyoshi

AU - Onaya, Toshimasa

PY - 1991/9

Y1 - 1991/9

N2 - The cellular distribution of parvalbumin-like immunoreactivity (PA-LI) in the human brain was investigated by peroxidase-antiperoxidase methods using antiserum to rat skeletal muscle parvalbumin. PA-LI was present in non-pyramidal neurons of the cerebral cortices, stellate cells, basket cells and Purkinje cells in cerebellar cortices, and neurons of some nuclei in human brain stem; the distribution of PA-LI in human brain was very similar to that in rat brain. These results indicate that PA-LI is widely distributed in a specific subpopulation of neurons of the human brain.

AB - The cellular distribution of parvalbumin-like immunoreactivity (PA-LI) in the human brain was investigated by peroxidase-antiperoxidase methods using antiserum to rat skeletal muscle parvalbumin. PA-LI was present in non-pyramidal neurons of the cerebral cortices, stellate cells, basket cells and Purkinje cells in cerebellar cortices, and neurons of some nuclei in human brain stem; the distribution of PA-LI in human brain was very similar to that in rat brain. These results indicate that PA-LI is widely distributed in a specific subpopulation of neurons of the human brain.

KW - Calcium-binding protein

KW - Immunohistochemistry

KW - Parvalbumin

UR - http://www.scopus.com/inward/record.url?scp=0025874192&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025874192&partnerID=8YFLogxK

U2 - 10.1007/BF00315329

DO - 10.1007/BF00315329

M3 - Article

C2 - 1940981

AN - SCOPUS:0025874192

VL - 238

SP - 320

EP - 322

JO - Journal of Neurology

JF - Journal of Neurology

SN - 0340-5354

IS - 6

ER -